CBX6 and PCGF6

Number of citations of the paper that reports this interaction (PMID 21282530)
11

Data Source:
BioGRID (pull down)

		CBX6	PCGF6
Gene Name		chromobox homolog 6	polycomb group ring finger 6
Image
Gene Ontology Annotations	Cellular Component	Heterochromatin Nucleus Nucleoplasm PcG Protein Complex	Nucleus PcG Protein Complex PRC1 Complex
	Molecular Function	Single-stranded RNA Binding Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Chromatin Modification	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated
Pathways		Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Bladder cancer ( 20972438)
Protein-Protein Interactions		9 interactors: BMI1 HOXC9 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 RING1 RNF2	16 interactors: BMI1 CBX6 CBX7 CBX8 CDK7 E2F6 HIST3H3 KDM5D PEX10 RAD18 RING1 RNF2 SS18L1 UBE2U USP2 USP21
Entrez ID		23466	84108
HPRD ID		13005	07427
Ensembl ID		ENSG00000183741	ENSG00000156374
Uniprot IDs		B0QXZ6 O95503	Q9BYE7
PDB IDs		3GV6 3I90	2DJB
Enriched GO Terms of Interacting Partners?		Histone Ubiquitination Transcription, DNA-templated RNA Biosynthetic Process Histone H2A Monoubiquitination Histone H2A Ubiquitination Anterior/posterior Pattern Specification RNA Metabolic Process Gene Expression Histone Monoubiquitination Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Histone Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Pattern Specification Process Protein Monoubiquitination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Protein Ubiquitination Chromatin Modification Protein Modification By Small Protein Conjugation Nitrogen Compound Metabolic Process Chromatin Organization Embryonic Skeletal System Morphogenesis Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryonic Skeletal System Development Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Embryonic Morphogenesis Skeletal System Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Organ Morphogenesis Organ Morphogenesis Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Embryo Development Embryonic Organ Development Histone H2A-K119 Monoubiquitination Histone Acetylation	Chromatin Modification Chromosome Organization Chromatin Organization Histone Ubiquitination Histone Modification Organelle Organization Negative Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Protein Ubiquitination Nitrogen Compound Metabolic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Cellular Protein Modification Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Histone H2A Monoubiquitination Macromolecule Biosynthetic Process Cellular Metabolic Process Histone H2A Ubiquitination Regulation Of Gene Expression Histone Monoubiquitination Cellular Protein Metabolic Process Biosynthetic Process Protein Monoubiquitination Regulation Of Metabolic Process DNA Metabolic Process Anterior/posterior Pattern Specification Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Metabolic Process Histone H2A-K119 Monoubiquitination Metabolic Process Positive Regulation Of Immature T Cell Proliferation In Thymus
Tagcloud ?		acetylase aldh1a3 belonging bipotent ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 polycomb progenitors silico smarca4 smarcd3 smarce1 subpopulations trithorax	attains cbx3 collaboration compacted copresence e2f6 e2fs entailing h2a hp1gamma integral l3mbtl1 l3mbtl2 marks mblr mbt monoubiquitination necessitated overlap polycomb prc1 prc1l4 rb1 repression repressive ring1 ring2 rnai
Tagcloud (Difference) ?		acetylase aldh1a3 belonging bipotent ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 progenitors silico smarca4 smarcd3 smarce1 subpopulations trithorax	attains cbx3 collaboration compacted copresence e2f6 e2fs entailing h2a hp1gamma integral l3mbtl1 l3mbtl2 marks mblr mbt monoubiquitination necessitated overlap prc1 prc1l4 rb1 repression repressive ring1 ring2 rnai
Tagcloud (Intersection) ?		polycomb