CBX6 and PCGF5

Number of citations of the paper that reports this interaction (PMID 21282530)
11

Data Source:
BioGRID (pull down)

		CBX6	PCGF5
Gene Name		chromobox homolog 6	polycomb group ring finger 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Heterochromatin Nucleus Nucleoplasm PcG Protein Complex	Nucleus Nucleolus Centrosome PcG Protein Complex
	Molecular Function	Single-stranded RNA Binding Protein Binding	Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Chromatin Modification	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Bladder cancer ( 20972438)
Protein-Protein Interactions		9 interactors: BMI1 HOXC9 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 RING1 RNF2	11 interactors: BCOR CBX6 CBX7 CBX8 PCGF1 PHC2 PRMT6 RING1 RNF2 TRAF2 TRIM8
Entrez ID		23466	84333
HPRD ID		13005	17825
Ensembl ID		ENSG00000183741	ENSG00000180628
Uniprot IDs		B0QXZ6 O95503	Q86SE9
PDB IDs		3GV6 3I90
Enriched GO Terms of Interacting Partners?		Histone Ubiquitination Transcription, DNA-templated RNA Biosynthetic Process Histone H2A Monoubiquitination Histone H2A Ubiquitination Anterior/posterior Pattern Specification RNA Metabolic Process Gene Expression Histone Monoubiquitination Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Histone Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Pattern Specification Process Protein Monoubiquitination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Protein Ubiquitination Chromatin Modification Protein Modification By Small Protein Conjugation Nitrogen Compound Metabolic Process Chromatin Organization Embryonic Skeletal System Morphogenesis Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryonic Skeletal System Development Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Embryonic Morphogenesis Skeletal System Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Organ Morphogenesis Organ Morphogenesis Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Embryo Development Embryonic Organ Development Histone H2A-K119 Monoubiquitination Histone Acetylation	Histone Ubiquitination Histone H2A Monoubiquitination Histone H2A Ubiquitination Chromatin Modification Chromatin Organization Histone Monoubiquitination Protein Ubiquitination Chromosome Organization Protein Modification By Small Protein Conjugation Protein Monoubiquitination Negative Regulation Of RNA Biosynthetic Process Histone Modification Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Gene Expression RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Organelle Organization RNA Metabolic Process Cellular Protein Modification Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Histone H3-K36 Methylation Nitrogen Compound Metabolic Process Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Histone H3-R2 Methylation Negative Regulation Of Tooth Mineralization Histone H2A-K119 Monoubiquitination Pattern Specification Process Axis Specification Cellular Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity
Tagcloud ?		acetylase aldh1a3 belonging bipotent ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 polycomb progenitors silico smarca4 smarcd3 smarce1 subpopulations trithorax	actg1 adaptin bacterium caenorhabditis cap1 chaffeensis colocalized cored cotransformation cox2 ehrlichia evading gga1 host igl igll1 morulae obligately phagocytes reconstitute reprogram survives tr tropism trp120 trp47 trps unc unc13d
Tagcloud (Difference) ?		acetylase aldh1a3 belonging bipotent ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 polycomb progenitors silico smarca4 smarcd3 smarce1 subpopulations trithorax	actg1 adaptin bacterium caenorhabditis cap1 chaffeensis colocalized cored cotransformation cox2 ehrlichia evading gga1 host igl igll1 morulae obligately phagocytes reconstitute reprogram survives tr tropism trp120 trp47 trps unc unc13d
Tagcloud (Intersection) ?