CLEC4M and ICAM3

Number of citations of the paper that reports this interaction (PMID 11257134)
68

Data Source:
HPRD (in vitro)

		CLEC4M	ICAM3
Gene Name		C-type lectin domain family 4, member M	intercellular adhesion molecule 3
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytoplasm Integral Component Of Plasma Membrane Membrane	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Mannose Binding Carbohydrate Binding ICAM-3 Receptor Activity Peptide Antigen Binding Virion Binding Metal Ion Binding Calcium-dependent Protein Binding	Receptor Binding Integrin Binding Protein Binding
	Biological Process	Endocytosis Leukocyte Cell-cell Adhesion Cell-cell Recognition Regulation Of Gene Expression Modulation By Virus Of Host Morphology Or Physiology Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Regulation Of Blood Coagulation Intracellular Signal Transduction Innate Immune Response Peptide Antigen Transport Intracellular Transport Of Virus	Cell Adhesion Single Organismal Cell-cell Adhesion Extracellular Matrix Organization Regulation Of Immune Response
Pathways			Integrin cell surface interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS			Crohn's disease ( 21102463)
Protein-Protein Interactions		3 interactors: CD209 ICAM3 ITGAM	10 interactors: APP CD209 CLEC4M EZR ITGAD ITGAL ITGB2 MSN PRKCQ ZBTB16
Entrez ID		10332	3385
HPRD ID		12060	00889
Ensembl ID		ENSG00000104938	ENSG00000076662
Uniprot IDs		B4E2Z5 H7BXU4 Q9H2X3	P32942
PDB IDs		1K9J 1SL6 1XAR 1XPH 1Z0Y 3JQH	1T0P
Enriched GO Terms of Interacting Partners?		Single Organismal Cell-cell Adhesion Cell Adhesion Regulation Of Immune System Process Microglia Development Peptide Antigen Transport Leukocyte Cell-cell Adhesion Ectodermal Cell Differentiation Extracellular Matrix Organization Extracellular Structure Organization Virion Attachment To Host Cell Adhesion Of Symbiont To Host Leukocyte Migration Involved In Inflammatory Response Macrophage Differentiation Modulation By Virus Of Host Morphology Or Physiology Ectoderm Development Viral Genome Replication Innate Immune Response Intracellular Transport Of Virus Cellular Extravasation Activated T Cell Proliferation Regulation Of Immune Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Neutrophil Chemotaxis Neutrophil Migration Granulocyte Chemotaxis Cell-cell Recognition Immune Response T Cell Proliferation Defense Response Toll-like Receptor 4 Signaling Pathway Peptide Transport Interaction With Host Glial Cell Development Leukocyte Chemotaxis Toll-like Receptor Signaling Pathway Lymphocyte Proliferation Myeloid Leukocyte Differentiation Mononuclear Cell Proliferation Leukocyte Proliferation Cell Recognition Integrin-mediated Signaling Pathway Amide Transport Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of T Cell Proliferation Cell Chemotaxis	Leukocyte Cell-cell Adhesion Single Organismal Cell-cell Adhesion Cell Adhesion Immune System Process Activated T Cell Proliferation Immune Response Peptide Antigen Transport Membrane To Membrane Docking T Cell Proliferation Virion Attachment To Host Cell Locomotion Cell Activation Regulation Of T Cell Activation Regulation Of Immune System Process Defense Response Adhesion Of Symbiont To Host Innate Immune Response Movement Of Cell Or Subcellular Component Cellular Localization Extracellular Matrix Organization Regulation Of Cell-cell Adhesion Lymphocyte Proliferation Extracellular Structure Organization Mononuclear Cell Proliferation Integrin-mediated Signaling Pathway Regulation Of Lymphocyte Activation Leukocyte Proliferation Cell Recognition Blood Coagulation Hemostasis Regulation Of T Cell Proliferation Regulation Of Cell Activation Heterotypic Cell-cell Adhesion Modulation By Virus Of Host Morphology Or Physiology Viral Genome Replication Intracellular Transport Of Virus Establishment Of Endothelial Barrier Regulation Of Body Fluid Levels Chemotaxis Positive Regulation Of T Cell Activation Wound Healing Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Adhesion Leukocyte Migration Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Endocytosis Positive Regulation Of Cell-cell Adhesion Response To Wounding Endothelial Cell Development T Cell Aggregation
Tagcloud ?		affinities apo assignment carbohydrates cd209l cd299 certainty compartments crd dc debate dendritic endocytic endosomal glcnac glycan glycans grabbing homologue integrin intercellular lectin mannose moieties oligosaccharides recycling releases reversibly signr	br ccl20 ccl3 ccl4 csf2 csf3 cxcl1 cxcl12 discordances extremities figf grew igfbp1 iib il1alpha il1beta il6 il8 lymphatic matrigel mmp1 mmp13 mmp9 mts6 plaur plgf tnfrsf18 vegfa vegfc
Tagcloud (Difference) ?		affinities apo assignment carbohydrates cd209l cd299 certainty compartments crd dc debate dendritic endocytic endosomal glcnac glycan glycans grabbing homologue integrin intercellular lectin mannose moieties oligosaccharides recycling releases reversibly signr	br ccl20 ccl3 ccl4 csf2 csf3 cxcl1 cxcl12 discordances extremities figf grew igfbp1 iib il1alpha il1beta il6 il8 lymphatic matrigel mmp1 mmp13 mmp9 mts6 plaur plgf tnfrsf18 vegfa vegfc
Tagcloud (Intersection) ?