C8orf33 and MCC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C8orf33	MCC
Description		chromosome 8 open reading frame 33	MCC regulator of Wnt signaling pathway
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Lamellipodium Cell Projection
	Molecular Function	Protein Binding	Protein Binding Signaling Receptor Activity
	Biological Process		Signal Transduction Negative Regulation Of Epithelial Cell Migration Wnt Signaling Pathway Establishment Of Protein Localization Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Adult body size ( 32376654) Brain cytoarchitecture ( 20308991) Cerebral amyloid angiopathy ( 25188341) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Femur bone mineral density x serum urate levels interaction ( 34046847) Height ( 31562340) Metabolite levels ( 23823483) Neurofibrillary tangles ( 31497858) Nicotine dependence symptom count ( 25555482) Triglyceride levels ( 32203549) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		50 interacting genes: AAMP ALAS1 APP BLOC1S2 BRD4 CEP70 CFTR CRELD2 DISC1 DVL3 EDRF1 EPS8 FAM9B FEZ1 FST FYN GIT1 GPRASP1 HAP1 HMBOX1 IKZF1 IMMT KBTBD7 KCTD6 KRTAP10-7 LZTS2 MAPK8IP2 MCC MDFI MRFAP1 NACC1 NGEF NOL7 PI4KA PICK1 PNMA1 RASSF1 SF3B2 TAOK1 TNIP1 TRIM23 TRIM41 TUBA1A TUBB2B WIZ ZC3H15 ZFP28 ZNF205 ZNF331 ZNF526	77 interacting genes: ALDOB ANP32B APP BAAT C8orf33 C8orf48 CBX5 CBX8 CCDC112 CCDC146 CCDC180 CCDC185 CCDC187 CDC14B CDK8 CDKL3 CEP57L1 CEP95 CFAP58 CYLC2 DNAAF4 DYNC1I1 ELOA ERBIN ESRRG FAM161A FGF16 FRAT2 GTF2E2 HEMGN HSD17B3 KAT5 KEAP1 KIF3C KIFC3 LRRC45 MSANTD3 MTNR1A NANS NEK2 NFKBIB NOL12 PCCA PNKP POLL PRPF18 RASAL2 RCOR3 SEC61B SFRP4 SLTM SLU7 SYT17 SYT6 TCEA2 TCEANC TGFB1 THAP7 TRMO TRMT2A TSHZ2 TSTD2 TXLNA UTP14C ZBTB48 ZNF12 ZNF189 ZNF202 ZNF264 ZNF3 ZNF35 ZNF417 ZNF438 ZNF497 ZNF543 ZNF648 ZNF792
Entrez ID		65265	4163
HPRD ID		07951	01157
Ensembl ID		ENSG00000182307	ENSG00000171444
Uniprot IDs		Q9H7E9	P23508
PDB IDs			6MTU 6MTV
Enriched GO Terms of Interacting Partners?		Cytoplasm Growth Cone Gamma-tubulin Binding Identical Protein Binding Protein Binding Regulation Of JNK Cascade Modulation Of Chemical Synaptic Transmission Ephrin Receptor Binding Negative Regulation Of Signaling Learning Growth Factor Receptor Binding Regulation Of Cell Communication Nucleus Negative Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Cell Projection Organization Postsynaptic Density Protein-containing Complex Binding Centrosome Regulation Of Cell Projection Organization Negative Regulation Of Signal Transduction Regulation Of Signal Transduction Neuron Projection Organization Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Cellular Component Organization Ephrin Receptor Signaling Pathway Dendritic Spine Maintenance Microtubule Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Dendritic Spine Maintenance Cytosol Golgi-associated Vesicle Membrane Regulation Of Postsynapse Organization Neuron Cellular Homeostasis Regulation Of Cytoskeleton Organization Neuron Migration Microtubule Cytoskeleton Cell Projection Organization Regulation Of Hydrogen Peroxide Metabolic Process Positive Regulation Of Neuron Projection Development Cellular Component Maintenance Regulation Of Microtubule-based Process Learning Or Memory Heparan Sulfate Proteoglycan Binding	Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Centrosome
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