C8orf33 and TAOK1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		C8orf33	TAOK1
Description		chromosome 8 open reading frame 33	TAO kinase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Plasma Membrane Microtubule Cytoskeleton Nuclear Body Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Alpha-tubulin Binding Protein Serine/threonine Kinase Activator Activity Tau Protein Binding Beta-tubulin Binding Tau-protein Kinase Activity Protein Serine Kinase Activity
	Biological Process		Microtubule Cytoskeleton Organization DNA Repair Apoptotic Process DNA Damage Response Negative Regulation Of Microtubule Depolymerization Mitotic G2 DNA Damage Checkpoint Signaling Central Nervous System Neuron Development Positive Regulation Of Stress-activated MAPK Cascade Regulation Of Actin Cytoskeleton Organization Positive Regulation Of JNK Cascade Regulation Of Cytoskeleton Organization Neuron Cellular Homeostasis Regulation Of Microtubule Cytoskeleton Organization Execution Phase Of Apoptosis
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs			Fostamatinib
Diseases
GWAS			A body shape index ( 34021172) Mean platelet volume ( 19110211 19820697 22139419 22423221 24026423 27863252 32888494) Platelet count ( 22139419 29066854 32888494) Red cell distribution width ( 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		50 interacting genes: AAMP ALAS1 APP BLOC1S2 BRD4 CEP70 CFTR CRELD2 DISC1 DVL3 EDRF1 EPS8 FAM9B FEZ1 FST FYN GIT1 GPRASP1 HAP1 HMBOX1 IKZF1 IMMT KBTBD7 KCTD6 KRTAP10-7 LZTS2 MAPK8IP2 MCC MDFI MRFAP1 NACC1 NGEF NOL7 PI4KA PICK1 PNMA1 RASSF1 SF3B2 TAOK1 TNIP1 TRIM23 TRIM41 TUBA1A TUBB2B WIZ ZC3H15 ZFP28 ZNF205 ZNF331 ZNF526	9 interacting genes: C8orf33 CSNK1E DYNC1I1 GEMIN7 LATS1 MAP2K3 MARK1 UBASH3A WT1
Entrez ID		65265	57551
HPRD ID		07951	15467
Ensembl ID		ENSG00000182307	ENSG00000160551
Uniprot IDs		Q9H7E9	Q7L7X3
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm Growth Cone Gamma-tubulin Binding Identical Protein Binding Protein Binding Regulation Of JNK Cascade Modulation Of Chemical Synaptic Transmission Ephrin Receptor Binding Negative Regulation Of Signaling Learning Growth Factor Receptor Binding Regulation Of Cell Communication Nucleus Negative Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Cell Projection Organization Postsynaptic Density Protein-containing Complex Binding Centrosome Regulation Of Cell Projection Organization Negative Regulation Of Signal Transduction Regulation Of Signal Transduction Neuron Projection Organization Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Cellular Component Organization Ephrin Receptor Signaling Pathway Dendritic Spine Maintenance Microtubule Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Dendritic Spine Maintenance Cytosol Golgi-associated Vesicle Membrane Regulation Of Postsynapse Organization Neuron Cellular Homeostasis Regulation Of Cytoskeleton Organization Neuron Migration Microtubule Cytoskeleton Cell Projection Organization Regulation Of Hydrogen Peroxide Metabolic Process Positive Regulation Of Neuron Projection Development Cellular Component Maintenance Regulation Of Microtubule-based Process Learning Or Memory Heparan Sulfate Proteoglycan Binding	Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Protein Kinase Activity Canonical Inflammasome Complex Assembly Kinase Activity Regulation Of Hippo Signaling Phosphorylation Protein Phosphorylation Cellular Response To Sorbitol Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Sm-like Protein Family Complex Regulation Of Organ Growth Negative Regulation Of Female Gonad Development Negative Regulation Of Glomerular Mesangial Cell Proliferation Inner Cell Mass Cell Fate Commitment Inner Cell Mass Cellular Morphogenesis Cytoplasm Cytosol Response To Sorbitol Hemi-methylated DNA-binding Metanephric S-shaped Body Morphogenesis
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