RAMP3 and NSF

Number of citations of the paper that reports this interaction (PubMedID 15613468)
0

Data Source:
BioGRID (far western blotting)

		RAMP3	NSF
Description		receptor activity modifying protein 3	N-ethylmaleimide sensitive factor, vesicle fusing ATPase
Image
GO Annotations	Cellular Component	Lysosome Plasma Membrane Cell Surface Membrane Receptor Complex Amylin Receptor Complex 3 Adrenomedullin Receptor Complex	Cytoplasm Lysosomal Membrane Golgi Apparatus Golgi Stack Cytosol Plasma Membrane Dendritic Shaft GABA-ergic Synapse Postsynaptic Specialization, Intracellular Component
	Molecular Function	Amyloid-beta Binding Adrenomedullin Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity	SNARE Binding Nucleotide Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Syntaxin-1 Binding Protein Kinase Binding Syntaxin Binding PDZ Domain Binding Ionotropic Glutamate Receptor Binding Protein-containing Complex Binding Metal Ion Binding ATP-dependent Protein Disaggregase Activity
	Biological Process	Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Protein Transport Receptor Internalization Cellular Response To Hormone Stimulus Cross-receptor Inhibition Within G Protein-coupled Receptor Heterodimer Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Amylin Receptor Signaling Pathway Positive Regulation Of CAMP/PKA Signal Transduction Amylin Receptor 3 Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Response To Amyloid-beta Adrenomedullin Receptor Signaling Pathway	Positive Regulation Of Receptor Recycling Potassium Ion Transport Intracellular Protein Transport Exocytosis Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Regulation Of Exocytosis SNARE Complex Disassembly Golgi To Plasma Membrane Protein Transport Plasma Membrane Fusion Positive Regulation Of Protein Catabolic Process
Pathways		G alpha (s) signalling events Calcitonin-like ligand receptors	COPII-mediated vesicle transport Trafficking of GluR2-containing AMPA receptors COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs		Pramlintide	1-Ethyl-Pyrrolidine-2,5-Dione
Diseases
GWAS		Hepatic lipid content in extreme obesity ( 25246029)	Alcohol use disorder (total score) ( 30336701) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical surface area (global PC1) ( 32198502) Cortical volume ( 32963231) General factor of neuroticism ( 30867560) Handedness (Left-handed vs. non-left-handed) ( 30980028) Handedness (Right-handed vs. non-right-handed) ( 30980028) Hemoglobin levels ( 32327693) Hypertrophic cardiomyopathy ( 33495596) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 30054594) Macular thickness ( 30535121) Male-pattern baldness ( 28196072) Parkinson's disease ( 21812969 19915575) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Reaction time ( 29844566) Refractive error ( 32231278) Sense of smell ( 26632684) Thyroid stimulating hormone levels ( 30367059)
Interacting Genes		15 interacting genes: CALCR CALCRL CYSRT1 HSPB3 KRTAP10-3 KRTAP5-3 KRTAP5-7 KRTAP5-9 KRTAP9-3 NBPF19 NOTCH2NLA NSF PDCD6IP SLC31A2 VIPR1	31 interacting genes: ARRB1 ASPSCR1 CD28 CEP126 DRD2 EIF3E ERG28 ESR1 FILNC1 FUNDC2 GABARAP GABARAPL2 GABBR1 GABBR2 GOSR1 GRIA2 GRIA3 LUC7L2 MEOX2 NAPA NAPG PLK2 PTPN9 RAMP3 RNF10 RPLP1 STX1A STX4 STX8 USO1 VAPA
Entrez ID		10268	4905
HPRD ID		05517	03380
Ensembl ID		ENSG00000122679	ENSG00000073969
Uniprot IDs		A4D2L1 O60896	A0A384MTI6 P46459
PDB IDs		6UUS 6UVA 7TZF 8F0K 8F2A 8F2B	6KZQ
Enriched GO Terms of Interacting Partners?		Intermediate Filament Calcitonin Receptor Activity Calcitonin Gene-related Peptide Receptor Activity Calcitonin Gene-related Peptide Receptor Signaling Pathway Calcitonin Family Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Amylin Receptor Complex 2 Calcitonin Family Receptor Activity Transmembrane Signaling Receptor Activity Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Amylin Receptor Complex 1 Calcitonin Binding Regulation Of Copper Ion Transmembrane Transport G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cellular Response To Sucrose Stimulus Amylin Receptor Complex 3 Extracellular Exosome Biogenesis Adrenomedullin Binding CGRP Receptor Complex Amylin Receptor 3 Signaling Pathway Amylin Receptor Activity SNARE Complex Disassembly Vasoactive Intestinal Polypeptide Receptor Activity Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity Proteinase Activated Receptor Binding Adrenomedullin Receptor Complex Adrenomedullin Receptor Activity Amylin Receptor 1 Signaling Pathway Amylin Receptor 2 Signaling Pathway Extracellular Vesicle Biogenesis Positive Regulation Of Extracellular Exosome Assembly Actomyosin Contractile Ring Assembly Keratin Filament G Protein-coupled Receptor Activity Postsynaptic Specialization, Intracellular Component Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Adrenomedullin Receptor Signaling Pathway Amylin Receptor Signaling Pathway Copper Ion Import ATP-dependent Protein Disaggregase Activity Regulation Of Extracellular Exosome Assembly Vascular Associated Smooth Muscle Cell Proliferation Response To Sucrose Response To Disaccharide Copper Ion Transmembrane Transporter Activity Maintenance Of Epithelial Cell Apical/basal Polarity	Membrane Fusion SNARE Complex Intracellular Protein Localization SNARE Binding Protein Transport Organelle Localization By Membrane Tethering Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Membrane Docking SNAP Receptor Activity Vesicle Fusion Establishment Of Protein Localization Chemical Synaptic Transmission Organelle Membrane Fusion Trans-synaptic Signaling Synaptic Signaling G Protein-coupled GABA Receptor Activity G Protein-coupled GABA Receptor Complex G Protein-coupled Receptor Heterodimeric Complex Organelle Fusion Intracellular Protein Transport Vesicle Docking Positive Regulation Of Synaptic Transmission Dendritic Spine Regulation Of Protein Localization To Cell Periphery GABA Receptor Complex Golgi Vesicle Transport Soluble NSF Attachment Protein Activity Regulation Of Protein Localization To Membrane Membrane Organization Negative Regulation Of Dopamine Secretion Vesicle Organization Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Modulation Of Chemical Synaptic Transmission Intracellular Transport Regulation Of Postsynaptic Membrane Potential Neuron-glial Cell Signaling Regulation Of Catecholamine Secretion Negative Regulation Of Synaptic Transmission Establishment Of Localization In Cell GABA Receptor Activity AMPA Glutamate Receptor Activity Postsynaptic Membrane Regulation Of Protein Localization To Plasma Membrane ATP-dependent Protein Binding Chloride Channel Inhibitor Activity Synaptic Transmission, Glutamatergic Cell-cell Signaling Syntaxin Binding Endomembrane System
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