RAMP3 and PDCD6IP

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		RAMP3	PDCD6IP
Gene Name		receptor (G protein-coupled) activity modifying protein 3	programmed cell death 6 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Lysosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex	Immunological Synapse Cytoplasm Microtubule Organizing Center Cytosol Focal Adhesion Membrane Vesicle Melanosome Extracellular Vesicular Exosome Endoplasmic Reticulum Exit Site
	Molecular Function	Receptor Activity Protein Binding Protein Transporter Activity Coreceptor Activity	Protein Binding SH3 Domain Binding Proteinase Activated Receptor Binding Protein Homodimerization Activity Calcium-dependent Protein Binding
	Biological Process	Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Protein Transport Receptor Internalization Negative Regulation Of Transcription, DNA-templated Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane	Cell Separation After Cytokinesis Apoptotic Process Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Viral Life Cycle Viral Budding Via Host ESCRT Complex Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Exosomal Secretion Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Extracellular Vesicular Exosome Assembly
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Calcitonin-like ligand receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)	HIV Life Cycle Budding and maturation of HIV virion Uptake and actions of bacterial toxins HIV Infection Uptake and function of anthrax toxins Late Phase of HIV Life Cycle
Drugs		Pramlintide
Diseases
GWAS			Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-Protein Interactions		10 interactors: CALCR CALCRL HSPB3 KRTAP10-3 KRTAP5-9 NOTCH2NL NSF PDCD6IP SLC31A2 VIPR1	35 interactors: ARRDC1 ARRDC3 ATN1 CD2AP CEP55 CHMP4A CHMP4B CHMP4C CXCR1 EGFR F2R GRB2 HOXA1 ITSN1 ITSN2 KEAP1 MAPK6 PDCD6 PTK2B RAMP3 RNF11 SDCBP SH3GL1 SH3GL2 SH3GL3 SH3KBP1 SH3RF1 SRC TAB1 TNIP2 TSG101 TTF2 VPS28 VPS37C YES1
Entrez ID		10268	10015
HPRD ID		05517	06425
Ensembl ID		ENSG00000122679	ENSG00000170248
Uniprot IDs		A4D2L1 O60896	C5MQH7 Q8WUM4
PDB IDs			2OEV 2OEW 2OEX 2OJQ 2R02 2R03 2R05 2XS1 2XS8 2ZNE 3C3O 3C3Q 3C3R 3E1R 4JJY
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Receptor Internalization Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of CAMP Biosynthetic Process Positive Regulation Of CAMP Metabolic Process Regulation Of Copper Ion Transmembrane Transport Cellular Response To Sucrose Stimulus Receptor Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Golgi Vesicle Docking Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Protein Localization To Plasma Membrane Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Exocytosis Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Extracellular Vesicular Exosome Assembly Viral Budding Via Host ESCRT Complex Plasma Membrane Organization Metal Ion Transport Membrane Organization Viral Budding Protein Localization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Copper Ion Transmembrane Transport Response To Sucrose Positive Regulation Of Receptor Recycling Cellular Copper Ion Homeostasis Cell Separation After Cytokinesis Plasma Membrane Fusion Receptor-mediated Endocytosis G-protein Coupled Receptor Signaling Pathway Protein Localization To Membrane Cation Transport Regulation Of Vesicle-mediated Transport CAMP Biosynthetic Process Copper Ion Homeostasis Virion Assembly Golgi To Plasma Membrane Protein Transport Positive Regulation Of Organelle Assembly Cellular Metal Ion Homeostasis Copper Ion Transport Endomembrane System Organization Regulation Of Receptor Recycling Cellular Cation Homeostasis	Virion Assembly Locomotion Endocytosis Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Cell Migration Cell Separation After Cytokinesis Membrane Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Axon Guidance Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Chemotaxis Viral Budding Transport Regulation Of Signal Transduction Viral Life Cycle Regulation Of Cellular Process Establishment Of Protein Localization Endosomal Transport Viral Protein Processing Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Axonogenesis Positive Regulation Of Cellular Metabolic Process Negative Regulation Of ERBB Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Signal Transduction Viral Process Axon Development Regulation Of Signaling Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Development Regulation Of MAPK Cascade Neuron Projection Morphogenesis Regulation Of Intracellular Signal Transduction Cell Projection Organization Response To Organic Substance Multicellular Organismal Development Regulation Of Organelle Organization Response To External Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vacuolar Transport Positive Regulation Of Metabolic Process Intracellular Transport Neuron Development Anatomical Structure Development Apoptotic Process Cell Morphogenesis Involved In Differentiation
Tagcloud ?		acidic amylin calcitonin calcr causally deltan glycolysis iapp implement interplay isoforms lymphomas manipulating p63 p73 pramlintide reactivation reprogramming resemble suppressive ta tap63 tap73 therapeutically thymic tp53 tp63 tp73 tumours	129n 146n adjuvanted arepanrix batch batches deamidation dige dioxidation fabp focetria gallus glycosylation h1n1 ha1 ha2 hemagglutinin latticed ma1 manufacturing narcolepsy neuraminidase nucleoprotein pandemrix ph1n1 sulfation tspan8 tub vaccines
Tagcloud (Difference) ?		acidic amylin calcitonin calcr causally deltan glycolysis iapp implement interplay isoforms lymphomas manipulating p63 p73 pramlintide reactivation reprogramming resemble suppressive ta tap63 tap73 therapeutically thymic tp53 tp63 tp73 tumours	129n 146n adjuvanted arepanrix batch batches deamidation dige dioxidation fabp focetria gallus glycosylation h1n1 ha1 ha2 hemagglutinin latticed ma1 manufacturing narcolepsy neuraminidase nucleoprotein pandemrix ph1n1 sulfation tspan8 tub vaccines
Tagcloud (Intersection) ?