RAMP3 and VIPR1

Number of citations of the paper that reports this interaction (PMID 12446722)
51

Data Source:
HPRD (in vitro)

		RAMP3	VIPR1
Gene Name		receptor (G protein-coupled) activity modifying protein 3	vasoactive intestinal peptide receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Lysosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Receptor Activity Protein Binding Protein Transporter Activity Coreceptor Activity	Vasoactive Intestinal Polypeptide Receptor Activity Protein Binding
	Biological Process	Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Protein Transport Receptor Internalization Negative Regulation Of Transcription, DNA-templated Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane	Muscle Contraction Immune Response G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Synaptic Transmission Digestion Positive Regulation Of Cell Proliferation
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Calcitonin-like ligand receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)	Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events
Drugs		Pramlintide
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CALCR CALCRL HSPB3 KRTAP10-3 KRTAP5-9 NOTCH2NL NSF PDCD6IP SLC31A2 VIPR1	15 interactors: ADCYAP1 CALM1 GNAI1 GNAQ GNAS GPRASP1 PFN1 PTMA RAMP1 RAMP2 RAMP3 SCT TINF2 VIP WASL
Entrez ID		10268	7433
HPRD ID		05517	01890
Ensembl ID		ENSG00000122679	ENSG00000114812
Uniprot IDs		A4D2L1 O60896	B4DNY6 P32241
PDB IDs			1OF2 1OGT 3B3I
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Receptor Internalization Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of CAMP Biosynthetic Process Positive Regulation Of CAMP Metabolic Process Regulation Of Copper Ion Transmembrane Transport Cellular Response To Sucrose Stimulus Receptor Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Golgi Vesicle Docking Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Protein Localization To Plasma Membrane Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Exocytosis Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Extracellular Vesicular Exosome Assembly Viral Budding Via Host ESCRT Complex Plasma Membrane Organization Metal Ion Transport Membrane Organization Viral Budding Protein Localization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Copper Ion Transmembrane Transport Response To Sucrose Positive Regulation Of Receptor Recycling Cellular Copper Ion Homeostasis Cell Separation After Cytokinesis Plasma Membrane Fusion Receptor-mediated Endocytosis G-protein Coupled Receptor Signaling Pathway Protein Localization To Membrane Cation Transport Regulation Of Vesicle-mediated Transport CAMP Biosynthetic Process Copper Ion Homeostasis Virion Assembly Golgi To Plasma Membrane Protein Transport Positive Regulation Of Organelle Assembly Cellular Metal Ion Homeostasis Copper Ion Transport Endomembrane System Organization Regulation Of Receptor Recycling Cellular Cation Homeostasis	Positive Regulation Of CAMP Biosynthetic Process Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Adenylate Cyclase Activity G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Lyase Activity G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Body Fluid Levels Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Platelet Activation Receptor Metabolic Process Cellular Localization Activation Of Adenylate Cyclase Activity Establishment Of Localization In Cell Secretion Transport Receptor Internalization Cell Surface Receptor Signaling Pathway Blood Coagulation Hemostasis Regulation Of Protein Localization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Membrane Organization Vesicle-mediated Transport Response To Hormone Regulation Of Phosphorus Metabolic Process Regulation Of Protein Glycosylation Positive Regulation Of Cellular Biosynthetic Process Wound Healing Negative Regulation Of Ion Transport Cell Activation Response To Wounding Protein Localization CAMP Biosynthetic Process Negative Regulation Of Potassium Ion Transport Regulation Of Signal Transduction Protein Localization To Plasma Membrane Response To Lipid Regulation Of Glycoprotein Biosynthetic Process Nitric Oxide Metabolic Process Response To Organic Cyclic Compound
Tagcloud ?		acidic amylin calcitonin calcr causally deltan glycolysis iapp implement interplay isoforms lymphomas manipulating p63 p73 pramlintide reactivation reprogramming resemble suppressive ta tap63 tap73 therapeutically thymic tp53 tp63 tp73 tumours	10k ac calca canonical cervix cervixes checkpoint differentially g2 genomics globally igfbp2 immunological krt17 networks oligomicroarray pheochromocytoma ppargamma rnas scc separated signature signatures splenomegaly transcriptomic transcripts urgent uterine utilized
Tagcloud (Difference) ?		acidic amylin calcitonin calcr causally deltan glycolysis iapp implement interplay isoforms lymphomas manipulating p63 p73 pramlintide reactivation reprogramming resemble suppressive ta tap63 tap73 therapeutically thymic tp53 tp63 tp73 tumours	10k ac calca canonical cervix cervixes checkpoint differentially g2 genomics globally igfbp2 immunological krt17 networks oligomicroarray pheochromocytoma ppargamma rnas scc separated signature signatures splenomegaly transcriptomic transcripts urgent uterine utilized
Tagcloud (Intersection) ?