RAMP3 and SLC31A2

Number of citations of the paper that reports this interaction (PubMedID 14722252)
0

Data Source:
BioGRID (pull down)

		RAMP3	SLC31A2
Description		receptor activity modifying protein 3	solute carrier family 31 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Plasma Membrane Cell Surface Membrane Receptor Complex Amylin Receptor Complex 3 Adrenomedullin Receptor Complex	Lysosome Lysosomal Membrane Endosome Late Endosome Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Late Endosome Membrane Recycling Endosome
	Molecular Function	Amyloid-beta Binding Adrenomedullin Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity	Copper Ion Transmembrane Transporter Activity Protein Binding
	Biological Process	Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Protein Transport Receptor Internalization Cellular Response To Hormone Stimulus Cross-receptor Inhibition Within G Protein-coupled Receptor Heterodimer Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Amylin Receptor Signaling Pathway Positive Regulation Of CAMP/PKA Signal Transduction Amylin Receptor 3 Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Response To Amyloid-beta Adrenomedullin Receptor Signaling Pathway	Monoatomic Ion Transport Copper Ion Transport Intracellular Copper Ion Homeostasis Copper Ion Import Copper Ion Transmembrane Transport Regulation Of Copper Ion Transmembrane Transport
Pathways		G alpha (s) signalling events Calcitonin-like ligand receptors
Drugs		Pramlintide
Diseases
GWAS		Hepatic lipid content in extreme obesity ( 25246029)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494)
Interacting Genes		15 interacting genes: CALCR CALCRL CYSRT1 HSPB3 KRTAP10-3 KRTAP5-3 KRTAP5-7 KRTAP5-9 KRTAP9-3 NBPF19 NOTCH2NLA NSF PDCD6IP SLC31A2 VIPR1	9 interacting genes: BNIP3 F2RL1 GPR35 HTR2B OPRL1 RAMP1 RAMP2 RAMP3 VKORC1
Entrez ID		10268	1318
HPRD ID		05517	04365
Ensembl ID		ENSG00000122679	ENSG00000136867
Uniprot IDs		A4D2L1 O60896	O15432 Q53X94
PDB IDs		6UUS 6UVA 7TZF 8F0K 8F2A 8F2B
Enriched GO Terms of Interacting Partners?		Intermediate Filament Calcitonin Receptor Activity Calcitonin Gene-related Peptide Receptor Activity Calcitonin Gene-related Peptide Receptor Signaling Pathway Calcitonin Family Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Amylin Receptor Complex 2 Calcitonin Family Receptor Activity Transmembrane Signaling Receptor Activity Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Amylin Receptor Complex 1 Calcitonin Binding Regulation Of Copper Ion Transmembrane Transport G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cellular Response To Sucrose Stimulus Amylin Receptor Complex 3 Extracellular Exosome Biogenesis Adrenomedullin Binding CGRP Receptor Complex Amylin Receptor 3 Signaling Pathway Amylin Receptor Activity SNARE Complex Disassembly Vasoactive Intestinal Polypeptide Receptor Activity Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity Proteinase Activated Receptor Binding Adrenomedullin Receptor Complex Adrenomedullin Receptor Activity Amylin Receptor 1 Signaling Pathway Amylin Receptor 2 Signaling Pathway Extracellular Vesicle Biogenesis Positive Regulation Of Extracellular Exosome Assembly Actomyosin Contractile Ring Assembly Keratin Filament G Protein-coupled Receptor Activity Postsynaptic Specialization, Intracellular Component Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Adrenomedullin Receptor Signaling Pathway Amylin Receptor Signaling Pathway Copper Ion Import ATP-dependent Protein Disaggregase Activity Regulation Of Extracellular Exosome Assembly Vascular Associated Smooth Muscle Cell Proliferation Response To Sucrose Response To Disaccharide Copper Ion Transmembrane Transporter Activity Maintenance Of Epithelial Cell Apical/basal Polarity	Amylin Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Calcitonin Family Receptor Signaling Pathway Adrenomedullin Receptor Activity Adrenomedullin Receptor Complex Amylin Receptor Activity Adrenomedullin Receptor Signaling Pathway Coreceptor Activity Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Calcium Ion Transport Receptor Internalization G Protein-coupled Receptor Activity Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Receptor-mediated Endocytosis Signal Transduction G-protein Alpha-subunit Binding Positive Regulation Of ERK1 And ERK2 Cascade Protein Localization To Plasma Membrane Receptor Complex Positive Regulation Of Protein-containing Complex Disassembly Metal Ion Transport Protein Localization To Cell Periphery Membrane Vascular Process In Circulatory System Regulation Of ERK1 And ERK2 Cascade Monoatomic Cation Transport Mitochondrion Autophagosome Adaptor Activity Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Circulatory System Process Positive Regulation Of Renin Secretion Into Blood Stream Nociceptin Receptor Activity Protein Localization To Membrane Calcitonin Gene-related Peptide Binding Cross-receptor Inhibition Within G Protein-coupled Receptor Heterodimer Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Cellular Response To Hormone Stimulus Regulation Of Biological Quality Monoatomic Ion Transport Proteinase-activated Receptor Activity Positive Regulation Of Eosinophil Degranulation Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Adrenomedullin Binding CGRP Receptor Complex Amylin Receptor Complex 3 Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Cellular Response To Cobalt Ion Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia
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