RAMP3 and HSPB3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RAMP3	HSPB3
Gene Name		receptor (G protein-coupled) activity modifying protein 3	heat shock 27kDa protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Lysosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex	Nucleus Cytoplasm
	Molecular Function	Receptor Activity Protein Binding Protein Transporter Activity Coreceptor Activity
	Biological Process	Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Protein Transport Receptor Internalization Negative Regulation Of Transcription, DNA-templated Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane	Response To Unfolded Protein
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Calcitonin-like ligand receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)
Drugs		Pramlintide
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CALCR CALCRL HSPB3 KRTAP10-3 KRTAP5-9 NOTCH2NL NSF PDCD6IP SLC31A2 VIPR1	18 interactors: ANP32A BBOX1 FAM127B HSPB2 HSPB8 LRIF1 LSM14B MED31 MED8 MRPL38 NSMF OLFML3 PRPF4B RAMP3 RBM48 SETDB1 UNC119 ZZEF1
Entrez ID		10268	8988
HPRD ID		05517	06861
Ensembl ID		ENSG00000122679	ENSG00000169271
Uniprot IDs		A4D2L1 O60896	Q12988 Q6ICS9
PDB IDs
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Receptor Internalization Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of CAMP Biosynthetic Process Positive Regulation Of CAMP Metabolic Process Regulation Of Copper Ion Transmembrane Transport Cellular Response To Sucrose Stimulus Receptor Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Golgi Vesicle Docking Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Protein Localization To Plasma Membrane Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Exocytosis Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Extracellular Vesicular Exosome Assembly Viral Budding Via Host ESCRT Complex Plasma Membrane Organization Metal Ion Transport Membrane Organization Viral Budding Protein Localization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Copper Ion Transmembrane Transport Response To Sucrose Positive Regulation Of Receptor Recycling Cellular Copper Ion Homeostasis Cell Separation After Cytokinesis Plasma Membrane Fusion Receptor-mediated Endocytosis G-protein Coupled Receptor Signaling Pathway Protein Localization To Membrane Cation Transport Regulation Of Vesicle-mediated Transport CAMP Biosynthetic Process Copper Ion Homeostasis Virion Assembly Golgi To Plasma Membrane Protein Transport Positive Regulation Of Organelle Assembly Cellular Metal Ion Homeostasis Copper Ion Transport Endomembrane System Organization Regulation Of Receptor Recycling Cellular Cation Homeostasis
Tagcloud ?		acidic amylin calcitonin calcr causally deltan glycolysis iapp implement interplay isoforms lymphomas manipulating p63 p73 pramlintide reactivation reprogramming resemble suppressive ta tap63 tap73 therapeutically thymic tp53 tp63 tp73 tumours	apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspa12a hspa12b hspa13 hspa14 hspa1l hspb10 hspb2 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1
Tagcloud (Difference) ?		acidic amylin calcitonin calcr causally deltan glycolysis iapp implement interplay isoforms lymphomas manipulating p63 p73 pramlintide reactivation reprogramming resemble suppressive ta tap63 tap73 therapeutically thymic tp53 tp63 tp73 tumours	apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspa12a hspa12b hspa13 hspa14 hspa1l hspb10 hspb2 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1
Tagcloud (Intersection) ?