GLYAT and GPRASP1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GLYAT	GPRASP1
Gene Name		glycine-N-acyltransferase	G protein-coupled receptor associated sorting protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Extracellular Vesicular Exosome	Cytoplasm
	Molecular Function	Transferase Activity, Transferring Acyl Groups Glycine N-acyltransferase Activity Glycine N-benzoyltransferase Activity	Protein Binding
	Biological Process	Glycine Metabolic Process Acyl-CoA Metabolic Process Xenobiotic Metabolic Process Response To Toxic Substance Monocarboxylic Acid Metabolic Process Small Molecule Metabolic Process	Endosome To Lysosome Transport G-protein Coupled Receptor Catabolic Process
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Conjugation of salicylate with glycine Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Conjugation of benzoate with glycine Phase II conjugation Conjugation of carboxylic acids Amino Acid conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS		Body mass (lean) ( 23108985)
Protein-Protein Interactions		5 interactors: GPRASP1 KRTAP10-8 NOTCH2NL PTN RBM48	47 interactors: ADRB1 ADRB2 AGTR1 ATXN7 C8orf33 CALCR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRIP1 CXCR2 F2R F2RL1 GLP1R GLYAT GRM1 GRM5 GRM8 HGH1 HMOX2 HTR7 LAMTOR5 LRP2 MAP7D1 MLNR MTF2 OFD1 OPRD1 OPRK1 OPRL1 OPRM1 OXTR PBK PER1 PFDN1 SNAPIN STMN2 TAC3 TACR1 TACR2 TACR3 TBXA2R TFG TRAF4 VIPR1
Entrez ID		10249	9737
HPRD ID		07603	02333
Ensembl ID		ENSG00000149124	ENSG00000198932
Uniprot IDs		Q6IB77	Q5JY77
PDB IDs
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Catabolic Process Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway	G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Synaptic Transmission Cytosolic Calcium Ion Homeostasis Regulation Of Smooth Muscle Contraction Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Response To Stimulus Cellular Metal Ion Homeostasis Cell-cell Signaling Positive Regulation Of Smooth Muscle Contraction Cellular Cation Homeostasis Cellular Ion Homeostasis Signaling Signal Transduction Metal Ion Homeostasis Cell Communication Blood Circulation Cellular Chemical Homeostasis Ion Homeostasis Response To Stimulus Neuropeptide Signaling Pathway Regulation Of Muscle Contraction G-protein Coupled Acetylcholine Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Cellular Homeostasis Chemical Homeostasis Regulation Of Blood Pressure Tachykinin Receptor Signaling Pathway Regulation Of Systemic Arterial Blood Pressure Opioid Receptor Signaling Pathway Regulation Of Vasoconstriction Positive Regulation Of Uterine Smooth Muscle Contraction Neurological System Process Homeostatic Process Regulation Of Cellular Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Blood Pressure Behavior Regulation Of CAMP Biosynthetic Process Sensory Perception Of Pain Regulation Of Secretion Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Regulation Of CAMP Metabolic Process Response To Abiotic Stimulus Regulation Of Adenylate Cyclase Activity
Tagcloud ?		34kda 5mg acceptor acceptors acylglycines acyltransferase benzoic benzoyl benzoylglycine carboxylic coa conjugates detoxification glycine hippurate homogeneity kcat km monkey nickel ovine rhesus salicylic serving solve unanswered x10 xenobiotic
Tagcloud (Difference) ?		34kda 5mg acceptor acceptors acylglycines acyltransferase benzoic benzoyl benzoylglycine carboxylic coa conjugates detoxification glycine hippurate homogeneity kcat km monkey nickel ovine rhesus salicylic serving solve unanswered x10 xenobiotic
Tagcloud (Intersection) ?