GLYAT and RBM48

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GLYAT	RBM48
Gene Name		glycine-N-acyltransferase	RNA binding motif protein 48
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Extracellular Vesicular Exosome	Nucleoplasm
	Molecular Function	Transferase Activity, Transferring Acyl Groups Glycine N-acyltransferase Activity Glycine N-benzoyltransferase Activity	RNA Binding
	Biological Process	Glycine Metabolic Process Acyl-CoA Metabolic Process Xenobiotic Metabolic Process Response To Toxic Substance Monocarboxylic Acid Metabolic Process Small Molecule Metabolic Process
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Conjugation of salicylate with glycine Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Conjugation of benzoate with glycine Phase II conjugation Conjugation of carboxylic acids Amino Acid conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS		Body mass (lean) ( 23108985)
Protein-Protein Interactions		5 interactors: GPRASP1 KRTAP10-8 NOTCH2NL PTN RBM48	50 interactors: ANXA7 APLP1 BID BTBD2 C11orf49 CCDC106 CDK5RAP2 CDKN1A CDKN2C COX17 ERH FAM118B FXYD6 GADD45G GLYAT GSE1 GSTO1 HSPB1 HSPB3 ID2 KPNA2 MAFG MAP7D1 MLLT3 MNAT1 MPHOSPH6 NUDT21 OSGEP PAFAH1B3 PCDHA4 PNP PPP1R8 PRG2 PSMD11 RAB27A RFC5 RPA2 SAT1 SERPINB9 SH3GL3 SMN1 SULT1E1 TAF9 TK1 TNFSF10 TRDMT1 TRIB3 VIM WDR33 ZNF24
Entrez ID		10249	84060
HPRD ID		07603	13173
Ensembl ID		ENSG00000149124	ENSG00000127993
Uniprot IDs		Q6IB77	B4DGJ6 B7Z2K5 Q5RL73
PDB IDs
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Catabolic Process Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway	Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Developmental Process Response To Stimulus Central Nervous System Development MRNA Polyadenylation Nucleoside Metabolic Process Negative Regulation Of Transferase Activity RNA Polyadenylation Regulation Of Cell Cycle Negative Regulation Of Protein Kinase Activity Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Apoptotic Process Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Kinase Activity Regulation Of Cell Cycle Phase Transition Response To Stress Negative Regulation Of Catalytic Activity Programmed Cell Death Negative Regulation Of Cellular Protein Metabolic Process Cell Death Death MRNA Processing Multicellular Organismal Development Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Cellular Response To DNA Damage Stimulus Response To Xenobiotic Stimulus Regulation Of Cellular Protein Metabolic Process Nervous System Development Negative Regulation Of Protein Metabolic Process Anatomical Structure Development Mitotic Cell Cycle Process Regulation Of Cell Cycle Process Cellular Metabolic Process Negative Regulation Of Protein Phosphorylation Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cellular Response To Stress Positive Regulation Of Cell Cycle Arrest
Tagcloud ?		34kda 5mg acceptor acceptors acylglycines acyltransferase benzoic benzoyl benzoylglycine carboxylic coa conjugates detoxification glycine hippurate homogeneity kcat km monkey nickel ovine rhesus salicylic serving solve unanswered x10 xenobiotic
Tagcloud (Difference) ?		34kda 5mg acceptor acceptors acylglycines acyltransferase benzoic benzoyl benzoylglycine carboxylic coa conjugates detoxification glycine hippurate homogeneity kcat km monkey nickel ovine rhesus salicylic serving solve unanswered x10 xenobiotic
Tagcloud (Intersection) ?