Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
HRSP12 and SERPINA5
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
HRSP12
SERPINA5
Gene Name
heat-responsive protein 12
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
Extracellular Vesicular Exosome
Acrosomal Membrane
Extracellular Region
Extracellular Space
External Side Of Plasma Membrane
Membrane
Platelet Alpha Granule
Platelet Dense Tubular Network
Protein C Inhibitor-TMPRSS7 Complex
Protein C Inhibitor-TMPRSS11E Complex
Protein C Inhibitor-PLAT Complex
Protein C Inhibitor-PLAU Complex
Protein C Inhibitor-thrombin Complex
Protein C Inhibitor-KLK3 Complex
Protein C Inhibitor-plasma Kallikrein Complex
Protein Complex
Extracellular Vesicular Exosome
Protein C Inhibitor-coagulation Factor V Complex
Protein C Inhibitor-coagulation Factor Xa Complex
Protein C Inhibitor-coagulation Factor XI Complex
Molecular Function
Endonuclease Activity
Deaminase Activity
Poly(A) RNA Binding
Retinoic Acid Binding
Protease Binding
Serine-type Endopeptidase Inhibitor Activity
Glycosaminoglycan Binding
Heparin Binding
Phosphatidylcholine Binding
Acrosin Binding
Biological Process
Regulation Of Translational Termination
Nucleic Acid Phosphodiester Bond Hydrolysis
Lipid Transport
Spermatogenesis
Fusion Of Sperm To Egg Plasma Membrane
Blood Coagulation
Negative Regulation Of Endopeptidase Activity
Pathways
Common Pathway
Intrinsic Pathway
Formation of Fibrin Clot (Clotting Cascade)
Drugs
Benzoic Acid
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
9 interactors:
COX2
DEAF1
HIVEP1
HPD
MDM2
SERPINA5
SPEN
TMEM176A
TRIB3
20 interactors:
ACR
COPS6
F10
F11
F2
FGA
FGB
FGG
HRSP12
KLK1
KLK2
KLK3
KLKB1
PIAS4
PLAT
PLAU
PROC
RCHY1
SEMG2
THBD
Entrez ID
10247
5104
HPRD ID
03924
03503
Ensembl ID
ENSG00000132541
ENSG00000188488
Uniprot IDs
P52758
B3KTV6
B4DDH1
B4DPC7
P05154
PDB IDs
1ONI
1LQ8
1PAI
2HI9
2OL2
2PAI
3DY0
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Fatty Acid Biosynthetic Process
Response To Light Stimulus
Cellular Response To UV
Maintenance Of Blood-brain Barrier
Cellular Response To UV-C
Cellular Response To Vitamin B1
Regulation Of Fatty Acid Metabolic Process
Response To Radiation
Cellular Response To Light Stimulus
Cellular Response To Organonitrogen Compound
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Response To Vitamin
Positive Regulation Of Nucleocytoplasmic Transport
Cellular Response To Oxygen Levels
Defense Response
Regulation Of Fat Cell Differentiation
Positive Regulation Of Fibroblast Growth Factor Production
Response To UV
Regulation Of Lipid Biosynthetic Process
Phosphatidylinositol-mediated Signaling
Learning
Cellular Response To Radiation
Positive Regulation Of Cellular Metabolic Process
Gamete Generation
Traversing Start Control Point Of Mitotic Cell Cycle
Negative Regulation Of Synaptic Transmission, Dopaminergic
Nicotinamide Metabolic Process
Positive Regulation Of Platelet-derived Growth Factor Production
Positive Regulation Of Intracellular Protein Transport
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of Cell Differentiation
Tyrosine Catabolic Process
Response To Vitamin B1
Response To Ether
Negative Regulation Of Dendritic Cell Differentiation
Response To Carbohydrate
Positive Regulation Of Brown Fat Cell Differentiation
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Blood Coagulation
Negative Regulation Of Coagulation
Negative Regulation Of Wound Healing
Regulation Of Blood Coagulation
Blood Coagulation
Hemostasis
Regulation Of Wound Healing
Regulation Of Body Fluid Levels
Wound Healing
Response To Wounding
Regulation Of Fibrinolysis
Blood Coagulation, Intrinsic Pathway
Plasminogen Activation
Fibrinolysis
Proteolysis
Protein Activation Cascade
Positive Regulation Of Fibrinolysis
Positive Regulation Of Heterotypic Cell-cell Adhesion
Peptidyl-glutamic Acid Carboxylation
Extracellular Matrix Organization
Extracellular Structure Organization
Negative Regulation Of Endothelial Cell Apoptotic Process
Protein Metabolic Process
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Zymogen Activation
Factor XII Activation
Positive Regulation Of Vasoconstriction
Regulation Of Substrate Adhesion-dependent Cell Spreading
Response To Stress
Regulation Of Endothelial Cell Apoptotic Process
Platelet Aggregation
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Vasoconstriction
Platelet Activation
Positive Regulation Of Exocytosis
Regulation Of Cell-substrate Adhesion
Platelet Degranulation
Negative Regulation Of Fibrinolysis
Acute Inflammatory Response
Plasma Kallikrein-kinin Cascade
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Peptide Hormone Secretion
Protein Processing
Positive Regulation Of Peptide Secretion
Extracellular Matrix Disassembly
Protein Polymerization
Positive Regulation Of Hormone Secretion
Negative Regulation Of Platelet Activation
Response To Calcium Ion
Tagcloud
?
across
agr2
assigned
differently
effector
endocrine
ergs
estradiol
exploitable
greb1
interpretation
menstrual
mirroring
pdzk1
pgr
premenopausal
progesterone
rankl
responsiveness
rhythm
runx1
tff1
tumours
varies
w1
w2
w3
windows
Tagcloud (Difference)
?
across
agr2
assigned
differently
effector
endocrine
ergs
estradiol
exploitable
greb1
interpretation
menstrual
mirroring
pdzk1
pgr
premenopausal
progesterone
rankl
responsiveness
rhythm
runx1
tff1
tumours
varies
w1
w2
w3
windows
Tagcloud (Intersection)
?