HRSP12 and TMEM176A

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		HRSP12	TMEM176A
Gene Name		heat-responsive protein 12	transmembrane protein 176A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Extracellular Vesicular Exosome	Integral Component Of Membrane
	Molecular Function	Endonuclease Activity Deaminase Activity Poly(A) RNA Binding
	Biological Process	Regulation Of Translational Termination Nucleic Acid Phosphodiester Bond Hydrolysis	Negative Regulation Of Dendritic Cell Differentiation
Pathways
Drugs		Benzoic Acid
Diseases
GWAS		Obesity-related traits ( 23251661)	Height ( 20881960 23563607)
Protein-Protein Interactions		9 interactors: COX2 DEAF1 HIVEP1 HPD MDM2 SERPINA5 SPEN TMEM176A TRIB3	4 interactors: HIVEP1 HRSP12 TGM2 VKORC1
Entrez ID		10247	55365
HPRD ID		03924	13635
Ensembl ID		ENSG00000132541	ENSG00000002933
Uniprot IDs		P52758	Q96HP8
PDB IDs		1ONI
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Fatty Acid Biosynthetic Process Response To Light Stimulus Cellular Response To UV Maintenance Of Blood-brain Barrier Cellular Response To UV-C Cellular Response To Vitamin B1 Regulation Of Fatty Acid Metabolic Process Response To Radiation Cellular Response To Light Stimulus Cellular Response To Organonitrogen Compound Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Response To Vitamin Positive Regulation Of Nucleocytoplasmic Transport Cellular Response To Oxygen Levels Defense Response Regulation Of Fat Cell Differentiation Positive Regulation Of Fibroblast Growth Factor Production Response To UV Regulation Of Lipid Biosynthetic Process Phosphatidylinositol-mediated Signaling Learning Cellular Response To Radiation Positive Regulation Of Cellular Metabolic Process Gamete Generation Traversing Start Control Point Of Mitotic Cell Cycle Negative Regulation Of Synaptic Transmission, Dopaminergic Nicotinamide Metabolic Process Positive Regulation Of Platelet-derived Growth Factor Production Positive Regulation Of Intracellular Protein Transport Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Cell Differentiation Tyrosine Catabolic Process Response To Vitamin B1 Response To Ether Negative Regulation Of Dendritic Cell Differentiation Response To Carbohydrate Positive Regulation Of Brown Fat Cell Differentiation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis	Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Salivary Gland Cavitation Vitamin K Metabolic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Regulation Of Translational Termination Peptidyl-glutamic Acid Carboxylation Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Mitochondrial Calcium Ion Homeostasis
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