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HRSP12 and HPD
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
HRSP12
HPD
Gene Name
heat-responsive protein 12
4-hydroxyphenylpyruvate dioxygenase
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
Extracellular Vesicular Exosome
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Endonuclease Activity
Deaminase Activity
Poly(A) RNA Binding
4-hydroxyphenylpyruvate Dioxygenase Activity
Metal Ion Binding
Biological Process
Regulation Of Translational Termination
Nucleic Acid Phosphodiester Bond Hydrolysis
L-phenylalanine Catabolic Process
Tyrosine Catabolic Process
Cellular Nitrogen Compound Metabolic Process
Small Molecule Metabolic Process
Oxidation-reduction Process
Pathways
Phenylalanine and tyrosine catabolism
Metabolism of amino acids and derivatives
Drugs
Benzoic Acid
Nitisinone
(1-Tert-Butyl-5-Hydroxy-1h-Pyrazol-4-Yl)-(6-Methanesulfonyl-4\'-Methoxy-2-Methyl-Biphenyl-3-Yl)-Methanone
Diseases
GWAS
Obesity-related traits (
23251661
)
Obesity-related traits (
23251661
)
Urinary metabolites (
21572414
)
Protein-Protein Interactions
9 interactors:
COX2
DEAF1
HIVEP1
HPD
MDM2
SERPINA5
SPEN
TMEM176A
TRIB3
4 interactors:
CDKN1A
HIVEP1
HRSP12
IKBKG
Entrez ID
10247
3242
HPRD ID
03924
02041
Ensembl ID
ENSG00000132541
ENSG00000158104
Uniprot IDs
P52758
P32754
PDB IDs
1ONI
3ISQ
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Fatty Acid Biosynthetic Process
Response To Light Stimulus
Cellular Response To UV
Maintenance Of Blood-brain Barrier
Cellular Response To UV-C
Cellular Response To Vitamin B1
Regulation Of Fatty Acid Metabolic Process
Response To Radiation
Cellular Response To Light Stimulus
Cellular Response To Organonitrogen Compound
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Response To Vitamin
Positive Regulation Of Nucleocytoplasmic Transport
Cellular Response To Oxygen Levels
Defense Response
Regulation Of Fat Cell Differentiation
Positive Regulation Of Fibroblast Growth Factor Production
Response To UV
Regulation Of Lipid Biosynthetic Process
Phosphatidylinositol-mediated Signaling
Learning
Cellular Response To Radiation
Positive Regulation Of Cellular Metabolic Process
Gamete Generation
Traversing Start Control Point Of Mitotic Cell Cycle
Negative Regulation Of Synaptic Transmission, Dopaminergic
Nicotinamide Metabolic Process
Positive Regulation Of Platelet-derived Growth Factor Production
Positive Regulation Of Intracellular Protein Transport
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of Cell Differentiation
Tyrosine Catabolic Process
Response To Vitamin B1
Response To Ether
Negative Regulation Of Dendritic Cell Differentiation
Response To Carbohydrate
Positive Regulation Of Brown Fat Cell Differentiation
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Fc-epsilon Receptor Signaling Pathway
Fc Receptor Signaling Pathway
Intestinal Epithelial Cell Maturation
Cellular Response To UV-B
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Stress-induced Premature Senescence
Regulation Of Gene Expression
Regulation Of Translational Termination
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Kinase Activity
Immune Response-regulating Signaling Pathway
Positive Regulation Of Kinase Activity
Mitotic Cell Cycle Arrest
Response To UV-B
Intestinal Epithelial Cell Development
Regulation Of Protein Metabolic Process
Regulation Of Protein Import Into Nucleus, Translocation
Positive Regulation Of Transferase Activity
Intestinal Epithelial Cell Differentiation
Epithelial Cell Maturation
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Activation Of NF-kappaB-inducing Kinase Activity
Response To Arsenic-containing Substance
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Cellular Senescence
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Positive Regulation Of NIK/NF-kappaB Signaling
Response To X-ray
Positive Regulation Of Protein Phosphorylation
Response To Hyperoxia
Regulation Of Protein Kinase Activity
Response To Corticosterone
B Cell Homeostasis
Regulation Of Kinase Activity
NIK/NF-kappaB Signaling
Response To Mineralocorticoid
Regulation Of NIK/NF-kappaB Signaling
Innate Immune Response
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Positive Regulation Of B Cell Proliferation
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Phosphorylation
Regulation Of Immune Response
Columnar/cuboidal Epithelial Cell Development
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Regulation Of DNA Biosynthetic Process
Positive Regulation Of Immune System Process
Positive Regulation Of Protein Modification Process
Negative Regulation Of Apoptotic Process
Tagcloud
?
agers
agricultural
compliance
conduct
conservation
describes
educational
eighty
farm
feasible
greatest
hcp
hearing
hpds
industrial
intention
junior
loud
multicomponent
noise
persuade
school
schools
senior
students
surveys
teen
working
yearly
Tagcloud (Difference)
?
agers
agricultural
compliance
conduct
conservation
describes
educational
eighty
farm
feasible
greatest
hcp
hearing
hpds
industrial
intention
junior
loud
multicomponent
noise
persuade
school
schools
senior
students
surveys
teen
working
yearly
Tagcloud (Intersection)
?