STX7 and VAMP8

Number of citations of the paper that reports this interaction (PMID 11278762)
20

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		STX7	VAMP8
Gene Name		syntaxin 7	vesicle-associated membrane protein 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Immunological Synapse Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Plasma Membrane Endomembrane System Integral Component Of Membrane Endocytic Vesicle SNARE Complex Early Endosome Membrane Vesicle Azurophil Granule Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Tertiary Granule	Cytoplasm Mitochondrion Lysosomal Membrane Early Endosome Cytosol Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Secretory Granule Membrane SNARE Complex Late Endosome Membrane Vesicle Azurophil Granule Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Mucin Granule
	Molecular Function	SNARE Binding SNAP Receptor Activity Chloride Channel Inhibitor Activity Syntaxin Binding	SNARE Binding SNAP Receptor Activity Chloride Channel Inhibitor Activity Syntaxin Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Intracellular Protein Transport Vesicle Fusion Vesicle Docking Organelle Localization Organelle Assembly Positive Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Plasma Membrane	Autophagic Vacuole Fusion Exocytosis Post-Golgi Vesicle-mediated Transport Endocytosis Vesicle Fusion Protein Transport Regulation Of Endocytosis SNARE Complex Assembly Eosinophil Degranulation Neutrophil Degranulation Viral Entry Into Host Cell Membrane Organization Mucus Secretion Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Secretion By Cell Positive Regulation Of Histamine Secretion By Mast Cell
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS			Prostate cancer ( 21743467)
Protein-Protein Interactions		13 interactors: ENTPD2 MAPK6 NAPA SNAP29 STX4 STX6 STX8 VAMP7 VAMP8 VPS11 VPS16 VPS18 VTI1B	12 interactors: CDC25A MLH1 NAPA SNAP23 SNAP25 STX1A STX3 STX4 STX7 UBE2G2 VAMP2 VAMP3
Entrez ID		8417	8673
HPRD ID		04449	04415
Ensembl ID			ENSG00000118640
Uniprot IDs		O15400	Q9BV40
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Membrane Fusion Organelle Fusion Protein Transport Establishment Of Protein Localization Vesicle Organization Protein Localization Intracellular Protein Transport Establishment Of Localization In Cell Vesicle-mediated Transport Intracellular Transport Post-Golgi Vesicle-mediated Transport Cellular Localization Golgi Vesicle Transport Membrane Organization Cellular Protein Localization SNARE Complex Assembly Exocytosis Regulation Of Protein Localization To Plasma Membrane Regulation Of Vesicle-mediated Transport Endosomal Transport Secretion By Cell Positive Regulation Of Regulated Secretory Pathway Secretion Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Regulation Of Exocytosis Regulation Of Regulated Secretory Pathway Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Cellular Component Organization Transport Regulation Of Protein Localization Positive Regulation Of Exocytosis Regulation Of SNARE Complex Assembly Autophagic Vacuole Fusion Vesicle Fusion With Golgi Apparatus Regulation Of Cellular Localization Vacuolar Transport Vesicle Docking Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Docking Positive Regulation Of Mast Cell Degranulation Interaction With Host Positive Regulation Of Hormone Secretion Positive Regulation Of Mast Cell Activation Cellular Protein Complex Assembly Organelle Organization Regulation Of Mast Cell Degranulation Endosome To Lysosome Transport	Vesicle Fusion Membrane Fusion Organelle Fusion Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Organization Neurotransmitter Secretion Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Levels Neurotransmitter Transport Vesicle Docking Membrane Docking Organelle Localization Synaptic Vesicle Transport Membrane Organization Establishment Of Organelle Localization Exocytosis Establishment Of Vesicle Localization Vesicle Localization Post-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Secretion By Cell Positive Regulation Of Synaptic Transmission Cell-cell Signaling Vesicle-mediated Transport Regulation Of Synaptic Transmission Synaptic Transmission Regulation Of Cellular Localization Cellular Localization Secretion Long-term Synaptic Potentiation Protein Transport Intracellular Protein Transport Establishment Of Protein Localization Organelle Organization Intracellular Transport Golgi Vesicle Transport Glutamate Secretion Regulation Of Secretion Cellular Protein Complex Assembly Protein Localization Regulation Of Exocytosis Regulation Of Protein Localization Regulation Of Synaptic Plasticity Cellular Protein Localization Calcium Ion-dependent Exocytosis Regulation Of Protein Localization To Plasma Membrane Regulation Of Insulin Secretion Regulation Of Synaptic Vesicle Priming Regulation Of Peptide Hormone Secretion Acid Secretion
Tagcloud ?		cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx3 stx4 stx6 stx8 synapse synapses syntaxin1b2 tumorigenic vamp3 vamp4 vesicle vti1b	3t3 adipocytes characterised complexes consists facet finding fulfil glut4 immunoprecipitation isoforms l1 others propose sds snap23 snare subcellular syntaxin4 systematic trafficking vamp2 vamp3 vamps vary vesicle vesicles
Tagcloud (Difference) ?		cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snares stx13 stx16 stx3 stx4 stx6 stx8 synapse synapses syntaxin1b2 tumorigenic vamp4 vti1b	3t3 adipocytes characterised complexes consists facet finding fulfil glut4 immunoprecipitation isoforms l1 others propose sds snap23 subcellular syntaxin4 systematic trafficking vamp2 vamps vary vesicles
Tagcloud (Intersection) ?		snare vamp3 vesicle