STX7 and MFF

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STX7	MFF
Description		syntaxin 7	mitochondrial fission factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Endocytic Vesicle SNARE Complex Early Endosome Membrane Vesicle Azurophil Granule Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome Tertiary Granule Secretory Vesicle	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Peroxisome Synaptic Vesicle Membrane Cytoplasmic Vesicle Mitochondrial Membrane Protein-containing Complex Synapse
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Intracellular Protein Transport Vesicle Fusion Vesicle-mediated Transport Vesicle Docking Organelle Localization Organelle Assembly Positive Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Plasma Membrane	Mitochondrial Fission Protein Targeting To Mitochondrion Mitochondrion Organization Peroxisome Fission Positive Regulation Of Mitochondrial Fission
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Cutaneous leishmaniasis ( 32830257) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Intraocular pressure ( 29617998) Refractive astigmatism ( 30306274)
Interacting Genes		52 interacting genes: ANKS6 AQP6 ARL13B CERS4 CISD2 CREB3 CREB3L1 CYBRD1 EBP ELOVL5 ENTPD2 FAM174A FAM210B FKBP7 GJC3 HSD17B11 HSD17B13 JAGN1 LIME1 LMNA MAPK6 MFF MGST3 MRM1 MTUS1 NAPA REEP1 RETREG3 RIC3 SAR1A SLC10A1 SLC10A6 SLC18A1 SLC35D4 SNAP29 STX1A STX2 STX6 STX8 TM4SF19 TMEM205 TMEM267 TMEM80 TMPRSS2 TMX2 VAMP7 VAMP8 VPS11 VPS16 VPS18 VTI1B ZFYVE27	107 interacting genes: ADIPOQ AGPAT4 AIG1 ANKRD46 APOD APOL2 AQP3 AQP6 ATP6V0B BET1 C14orf180 C1QL4 C3orf52 CD79A CDIPT CEND1 CLDN19 CMTM5 CNIH1 COL4A5 CTXN3 CXCL16 CYB5B CYBC1 DNM1L ERGIC3 FAM209A FAM210B FAM3C FATE1 FCER1G FDCSP FXYD6 GJB1 GKN1 GOSR2 GPR152 IGFBP5 JAGN1 LAT LHFPL5 LPAR3 MEOX2 MIP MMGT1 MOSPD3 MPZL1 MTNR1B NIPAL3 NRM NTS OPN1SW OPRM1 PLK3 PLLP PLN PLP1 RAET1L RETREG3 RHBDL1 SACM1L SEC11C SEC22A SEC22B SEC23A SERINC2 SHISAL1 SLC18A3 SLC35B1 SLC41A2 SLC7A1 SLC7A14 SLC7A8 SMIM1 STRIT1 STX7 STX8 TEX264 TFRC TM6SF1 TMEM128 TMEM140 TMEM14C TMEM201 TMEM218 TMEM229B TMEM237 TMEM254 TMEM42 TMEM60 TMEM86B TMEM88 TMEM97 TMX2 TRAF3 TRAF3IP3 TRAM1L1 TRARG1 TSPAN2 TSPAN33 TSPO2 UBC UNC50 UNC93B1 UPK1B VAMP4 ZFPL1
Entrez ID		8417	56947
HPRD ID		04449	16653
Ensembl ID		ENSG00000079950	ENSG00000168958
Uniprot IDs		O15400	A0A0A0MS29 A0A9H3ZVE5 A0A9L9PY92 H7C433 Q9GZY8
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Membrane Fusion Vesicle Fusion Membrane Fusion SNAP Receptor Activity Organelle Fusion SNARE Complex Organelle Localization By Membrane Tethering Membrane Membrane Docking Vesicle Organization Syntaxin Binding Vesicle Docking Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNARE Binding Chloride Channel Inhibitor Activity Membrane Organization Establishment Of Protein Localization Protein Transport Autophagosome Maturation Intracellular Protein Transport CORVET Complex Organelle Localization Vesicle-mediated Transport Endomembrane System Lysosomal Membrane Intracellular Protein Localization Autophagy Protein Binding Protein-containing Complex Disassembly Vesicle Docking Involved In Exocytosis Establishment Of Localization In Cell Late Endosome Membrane HOPS Complex Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Organelle Organization Endosome To Lysosome Transport Steroid Dehydrogenase Activity Cellular Localization Endoplasmic Reticulum Tubular Network Organization Exocytosis Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Cytoplasmic Vesicle Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Positive Regulation Of Histamine Secretion By Mast Cell Vesicle Tethering Complex Recycling Endosome Presynaptic Active Zone Membrane	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding SNAP Receptor Activity SNARE Complex Golgi Membrane Mitochondrial Outer Membrane Endomembrane System Membrane Fusion Water Channel Activity Vesicle-mediated Transport Magnesium Ion Transmembrane Transporter Activity Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Magnesium Ion Transmembrane Transport Plasma Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Magnesium Ion Transport Organelle Fusion Transmembrane Transport Protein Localization To Plasma Membrane Membrane Organization Nuclear Inner Membrane Vesicle Fusion Regulation Of Protein Transport Cellular Localization Regulation Of Cellular Localization Water Transport Golgi Apparatus Organelle Membrane Fusion ER To Golgi Transport Vesicle Membrane Protein Localization To Cell Periphery Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Cone Photoreceptor Outer Segment Chloride Channel Inhibitor Activity Inorganic Cation Transmembrane Transporter Activity Vesicle Organization Myelin Sheath Amino Acid Transmembrane Transporter Activity Negative Regulation Of Protein Transport Renal Water Transport Myeloid Cell Differentiation Neutrophil Differentiation Cobalt Ion Transport
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