STX7 and TMEM205

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STX7	TMEM205
Description		syntaxin 7	transmembrane protein 205
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Endocytic Vesicle SNARE Complex Early Endosome Membrane Vesicle Azurophil Granule Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome Tertiary Granule Secretory Vesicle	Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding	Protein Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Intracellular Protein Transport Vesicle Fusion Vesicle-mediated Transport Vesicle Docking Organelle Localization Organelle Assembly Positive Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Cutaneous leishmaniasis ( 32830257) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		52 interacting genes: ANKS6 AQP6 ARL13B CERS4 CISD2 CREB3 CREB3L1 CYBRD1 EBP ELOVL5 ENTPD2 FAM174A FAM210B FKBP7 GJC3 HSD17B11 HSD17B13 JAGN1 LIME1 LMNA MAPK6 MFF MGST3 MRM1 MTUS1 NAPA REEP1 RETREG3 RIC3 SAR1A SLC10A1 SLC10A6 SLC18A1 SLC35D4 SNAP29 STX1A STX2 STX6 STX8 TM4SF19 TMEM205 TMEM267 TMEM80 TMPRSS2 TMX2 VAMP7 VAMP8 VPS11 VPS16 VPS18 VTI1B ZFYVE27	16 interacting genes: ARL6IP6 BNIP3 COMT FXYD6-FXYD2 GOSR2 NDUFA3 PLN SMAGP STX6 STX7 STX8 TMEM11 TMEM140 TREX1 VAMP4 VRK2
Entrez ID		8417	374882
HPRD ID		04449	18605
Ensembl ID		ENSG00000079950	ENSG00000105518
Uniprot IDs		O15400	Q6UW68
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Membrane Fusion Vesicle Fusion Membrane Fusion SNAP Receptor Activity Organelle Fusion SNARE Complex Organelle Localization By Membrane Tethering Membrane Membrane Docking Vesicle Organization Syntaxin Binding Vesicle Docking Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNARE Binding Chloride Channel Inhibitor Activity Membrane Organization Establishment Of Protein Localization Protein Transport Autophagosome Maturation Intracellular Protein Transport CORVET Complex Organelle Localization Vesicle-mediated Transport Endomembrane System Lysosomal Membrane Intracellular Protein Localization Autophagy Protein Binding Protein-containing Complex Disassembly Vesicle Docking Involved In Exocytosis Establishment Of Localization In Cell Late Endosome Membrane HOPS Complex Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Organelle Organization Endosome To Lysosome Transport Steroid Dehydrogenase Activity Cellular Localization Endoplasmic Reticulum Tubular Network Organization Exocytosis Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Cytoplasmic Vesicle Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Positive Regulation Of Histamine Secretion By Mast Cell Vesicle Tethering Complex Recycling Endosome Presynaptic Active Zone Membrane	SNARE Complex SNAP Receptor Activity Organelle Fusion Vesicle Organization SNARE Binding Vesicle Vesicle Fusion Organelle Membrane Fusion Synaptic Vesicle To Endosome Fusion Membrane Membrane Fusion Syntaxin Binding Membrane Organization Chloride Channel Inhibitor Activity Vesicle Docking Organelle Localization By Membrane Tethering Phagocytic Vesicle Membrane Docking Establishment Of Protein Localization Endomembrane System Regulation Of Protein Localization To Plasma Membrane Recycling Endosome Protein Transport Response To Oxidative Stress Regulation Of Protein Localization To Cell Periphery Vesicle-mediated Transport Regulation Of Protein Localization To Membrane Mitochondrial Membrane Trans-Golgi Network Cellular Response To Oxidative Stress Mitochondrion Autophagosome Adaptor Activity Norepinephrine Secretion Catechol O-methyltransferase Activity Circadian Sleep/wake Cycle, Sleep Phospholamban Complex Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Organelle Envelope Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Organelle Organization Nuclear Envelope Visual Learning Regulation Of Cellular Localization Intracellular Protein Transport Endoplasmic Reticulum Cellular Response To Chemical Stress Establishment Of Localization In Cell Cellular Response To Phosphate Starvation Visual Behavior
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