PARP3 and HIST1H1A

Number of citations of the paper that reports this interaction (PMID 20064938)
22

Data Source:
BioGRID (enzymatic study)

		PARP3	HIST1H1A
Gene Name		poly (ADP-ribose) polymerase family, member 3	histone cluster 1, H1a
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Centriole Site Of Double-strand Break	Nucleosome Nuclear Chromatin Nuclear Euchromatin
	Molecular Function	Catalytic Activity NAD+ ADP-ribosyltransferase Activity	Protein Binding Chromatin DNA Binding
	Biological Process	Telomere Maintenance DNA Repair Double-strand Break Repair Protein ADP-ribosylation Positive Regulation Of DNA Ligation Regulation Of Mitotic Spindle Organization Protein Localization To Site Of Double-strand Break	Nucleosome Assembly Spermatogenesis
Pathways			DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Activation of DNA fragmentation factor Apoptosis induced DNA fragmentation Cellular Senescence Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: APP HIST1H1A PARP1	45 interactors: AEBP2 CCNA1 CCNA2 CCNB1 CCND2 CCNE1 CDK1 CDK2 CDK4 CDK6 CDK7 CDKN1B CRP CTCFL EED EHMT2 EP300 EZH2 GADD45A GZMA IRAK4 KAT2B LIMK1 LIMK2 LOX NAP1L4 NASP PARP1 PARP3 PELP1 PKN1 PRDM1 PRKCA PRKCB PRKCD PRKCE PRKCZ PRKDC PTMA RBBP4 SUZ12 TERF1 TERF2IP TLK1 WHSC1L1
Entrez ID		10039	3024
HPRD ID		06370	00820
Ensembl ID		ENSG00000041880	ENSG00000124610
Uniprot IDs		Q9Y6F1	Q02539
PDB IDs		2EOC 3C49 3C4H 3CE0 3FHB 4GV0 4GV2 4GV4
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Growth Rate Protein Poly-ADP-ribosylation Regulation Of Binding Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Response To Oxidative Stress DNA Damage Response, Detection Of DNA Damage Positive Regulation Of Transcription Regulatory Region DNA Binding Neuron Remodeling Protein Autoprocessing Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of Growth Regulation Of SMAD Protein Import Into Nucleus Cellular Copper Ion Homeostasis Macrophage Differentiation Cellular Response To Superoxide Copper Ion Homeostasis Suckling Behavior Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Sexual Reproduction Response To Superoxide Protein ADP-ribosylation Response To Oxygen Radical Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Signal Transduction Involved In Regulation Of Gene Expression Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Positive Regulation Of DNA Binding Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Reproduction Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development	Chromosome Organization Cell Cycle Chromatin Organization Chromatin Modification Regulation Of Cell Cycle Organelle Organization Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Histone Modification Regulation Of Metabolic Process Mitotic Cell Cycle Process Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Kinase Activity Regulation Of Phosphorylation Regulation Of Nitrogen Compound Metabolic Process Cellular Protein Metabolic Process G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Phosphorus Metabolic Process Protein Phosphorylation Regulation Of Mitotic Cell Cycle Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Cell Division Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Cycle DNA Metabolic Process Cellular Response To Stress Response To Stress Histone Phosphorylation Regulation Of Catalytic Activity Peptidyl-amino Acid Modification Cellular Metabolic Process Regulation Of Cell Cycle Process Phosphorylation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression, Epigenetic
Tagcloud ?		2bs a549 activators afford apoptotic balance bimodal cdc7 ddit4 debated downregulated downregulating ep300 exerted genotoxic h1299 immortalized maintains mcf7 mechanistically microrna micrornaome mir modulators nih3t3 notion participation recognizing utr
Tagcloud (Difference) ?		2bs a549 activators afford apoptotic balance bimodal cdc7 ddit4 debated downregulated downregulating ep300 exerted genotoxic h1299 immortalized maintains mcf7 mechanistically microrna micrornaome mir modulators nih3t3 notion participation recognizing utr
Tagcloud (Intersection) ?