PARP3

Gene Name		poly (ADP-ribose) polymerase family, member 3
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Gene Ontology Annotations	Cellular Component	Nucleus Centriole Site Of Double-strand Break
	Molecular Function	Catalytic Activity NAD+ ADP-ribosyltransferase Activity
	Biological Process	Telomere Maintenance DNA Repair Double-strand Break Repair Protein ADP-ribosylation Positive Regulation Of DNA Ligation Regulation Of Mitotic Spindle Organization Protein Localization To Site Of Double-strand Break
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: APP HIST1H1A PARP1
Entrez ID		10039
HPRD ID		06370
Ensembl ID		ENSG00000041880
Uniprot IDs		Q9Y6F1
PDB IDs		2EOC 3C49 3C4H 3CE0 3FHB 4GV0 4GV2 4GV4
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Growth Rate Protein Poly-ADP-ribosylation Regulation Of Binding Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Response To Oxidative Stress DNA Damage Response, Detection Of DNA Damage Positive Regulation Of Transcription Regulatory Region DNA Binding Neuron Remodeling Protein Autoprocessing Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of Growth Regulation Of SMAD Protein Import Into Nucleus Cellular Copper Ion Homeostasis Macrophage Differentiation Cellular Response To Superoxide Copper Ion Homeostasis Suckling Behavior Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Sexual Reproduction Response To Superoxide Protein ADP-ribosylation Response To Oxygen Radical Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Signal Transduction Involved In Regulation Of Gene Expression Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Positive Regulation Of DNA Binding Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Reproduction Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development
Tagcloud ?		2bs a549 activators afford apoptotic balance bimodal cdc7 ddit4 debated downregulated downregulating ep300 exerted genotoxic h1299 immortalized maintains mcf7 mechanistically microrna micrornaome mir modulators nih3t3 notion participation recognizing utr