TROAP and GIGYF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TROAP	GIGYF1
Description		trophinin associated protein	GRB10 interacting GYF protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytosol Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Cell Adhesion	Insulin-like Growth Factor Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Autoimmune thyroid disease ( 32581359) LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Resting heart rate ( 27798624)
Interacting Genes		18 interacting genes: ACTMAP BANP BYSL DYNLT1 DYRK1A DYRK1B GIGYF1 KRT31 KRT40 KRT8 NBPF19 NOTCH2NLA OIP5 SSC4D TP53BP2 TRAF2 TRIM23 TRO	33 interacting genes: AIRIM ANKRD10 ARMC7 ATN1 CBX8 CCDC57 CNOT9 CRACR2A ENKD1 FAM124B GRB10 GRB14 GRB7 KAT5 KIFC3 MCRS1 MNS1 NEK6 NFKBID PRKAA2 PRR35 RBM22 SCAF8 SCNM1 SMARCD1 SNRPB SNRPC SPAG8 STAC3 TCEA2 TLE5 TROAP TSHZ2
Entrez ID		10024	64599
HPRD ID		04849	10145
Ensembl ID		ENSG00000135451	ENSG00000146830
Uniprot IDs		F8W130 Q12815	O75420
PDB IDs			5NVK 7RUQ
Enriched GO Terms of Interacting Partners?			Nucleoplasm Spliceosomal Complex Negative Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Insulin Receptor Signaling Pathway Lipid Droplet Disassembly Phosphatidylethanolamine Biosynthetic Process Positive Regulation Of DNA Repair Spindle Pole Protein Binding Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cellular Response To Insulin Stimulus Insulin Receptor Signaling Pathway MRNA Splicing, Via Spliceosome U2-type Prespliceosome RNA Splicing U1 SnRNP Microtubule-based Process RNA Splicing, Via Transesterification Reactions Phosphatidylcholine Biosynthetic Process Regulation Of DNA Repair MRNA Metabolic Process Histone Acetyltransferase Complex Axonemal A Tubule Inner Sheath Positive Regulation Of Cation Channel Activity
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