TROAP and KRT8

Number of citations of the paper that reports this interaction (PMID 9560222)
17

Data Source:
BioGRID (pull down)

		TROAP	KRT8
Gene Name		trophinin associated protein	keratin 8, type II
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytoplasm Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding Protein Complex Binding Scaffold Protein Binding
	Biological Process	Cell Adhesion	Viral Process Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process
Pathways
Drugs
Diseases
GWAS			Prostate cancer ( 21743057)
Protein-Protein Interactions		13 interactors: BANP BYSL DYNLT1 DYRK1A DYRK1B KRT31 KRT40 KRT8 MAPRE1 MAPRE3 TRAF2 TRIM23 TRO	35 interactors: ANXA1 BYSL DEDD DMD EGFR FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT17 KRT18 KRT31 KRT38 KRT40 MAPK1 MAPK14 MAPK3 MAPK8 PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 SUMO1 SUMO2 SUMO3 TCHP TFIP11 TROAP
Entrez ID		10024	3856
HPRD ID		04849	01015
Ensembl ID		ENSG00000135451	ENSG00000170421
Uniprot IDs		F8VSF9 Q12815	P05787 Q7L4M3
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Microtubule Plus-end Binding Positive Regulation Of Protein Binding Positive Regulation Of Binding Regulation Of Protein Binding Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Binding Cell Cycle Mitotic Cell Cycle Mitotic Nuclear Division Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Cellular Response To Tumor Necrosis Factor Cell Division Developmental Process Response To Tumor Necrosis Factor Viral Process Intracellular Transport Of Viral Protein In Host Cell Negative Regulation Of Glial Cell Apoptotic Process Multicellular Organismal Development Response To Hydrostatic Pressure Protein Localization To Microtubule Mitotic Cell Cycle Process	Neurotrophin TRK Receptor Signaling Pathway MAPK Cascade Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Tissue Development Fc Receptor Signaling Pathway Signal Transduction By Phosphorylation Apoptotic Process Positive Regulation Of Protein Metabolic Process Programmed Cell Death Innate Immune Response Cell Death Death Immune Response-regulating Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Kinase Activity Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Response To Organic Substance Positive Regulation Of Transferase Activity MyD88-dependent Toll-like Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Cellular Response To Lipid Response To Growth Factor Anatomical Structure Development Epidermal Growth Factor Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Defense Response Developmental Process Epithelium Development Response To Abiotic Stimulus Regulation Of Immune Response Positive Regulation Of Protein Kinase Activity Cellular Response To Fibroblast Growth Factor Stimulus Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process
Tagcloud ?		adenocarcinomas aimed biomarkers blot capg carcinomas clu deceased differently expressed expressions ihc immunohistochemistry insufficient itgb3 localize microarray muc5b none ovarian prame prediction prognostic qpcr semiquantitative serous survivors tacc1 tumors	ccna1 cdh1 circulatory code cohorts ctnnb1 differentially erbb2 explain favorable gata3 gli1 grouped hic1 highlighting interconnected ipa jun mki67 modulate notch1 predicts ptgs2 rassf1 regulators sfn transducers trigger triple
Tagcloud (Difference) ?		adenocarcinomas aimed biomarkers blot capg carcinomas clu deceased differently expressed expressions ihc immunohistochemistry insufficient itgb3 localize microarray muc5b none ovarian prame prediction prognostic qpcr semiquantitative serous survivors tacc1 tumors	ccna1 cdh1 circulatory code cohorts ctnnb1 differentially erbb2 explain favorable gata3 gli1 grouped hic1 highlighting interconnected ipa jun mki67 modulate notch1 predicts ptgs2 rassf1 regulators sfn transducers trigger triple
Tagcloud (Intersection) ?