GIGYF1 and RQCD1

Number of citations of the paper that reports this interaction (PMID 20878056)
2

Data Source:
BioGRID (affinity chromatography technology, pull down)

		GIGYF1	RQCD1
Gene Name		GRB10 interacting GYF protein 1	RCD1 required for cell differentiation1 homolog (S. pombe)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasmic MRNA Processing Body Nucleus Cytosol Membrane CCR4-NOT Complex
	Molecular Function		Protein Binding Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Insulin-like Growth Factor Receptor Signaling Pathway	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Translation Sex Differentiation Gene Expression Cytokine-mediated Signaling Pathway Gene Silencing By RNA Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Pathways			Deadenylation of mRNA Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ATN1 EIF4E2 GRB10 RQCD1	6 interactors: AKT1 EGFR GIGYF1 GIGYF2 GRB10 MYB
Entrez ID		64599	9125
HPRD ID		10145	08828
Ensembl ID		ENSG00000146830	ENSG00000144580
Uniprot IDs		O75420	B5MDQ4 B7Z1E5 D5MQE1 Q92600
PDB IDs			2FV2
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Translation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Glucose Import Cellular Response To Organic Substance Maintenance Of Cell Polarity Cytokine-mediated Signaling Pathway Posttranscriptional Regulation Of Gene Expression Toxin Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Glucose Transport Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Insulin-like Growth Factor Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Regulation Of Intracellular Estrogen Receptor Signaling Pathway Nuclear-transcribed MRNA Poly(A) Tail Shortening Response To Organic Substance Response To Cytokine Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Glycogen Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Neuron Apoptotic Process Regulation Of Metabolic Process Gene Silencing By RNA Regulation Of Insulin Receptor Signaling Pathway Regulation Of Glucose Import Gene Expression Neuron Death Negative Regulation Of Signal Transduction Cellular Macromolecule Biosynthetic Process Regulation Of Generation Of Precursor Metabolites And Energy Macromolecule Biosynthetic Process MRNA 3'-end Processing Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Signaling Negative Regulation Of Translation Regulation Of Glucose Transport Gene Silencing Regulation Of Glucose Metabolic Process RNA 3'-end Processing	Insulin-like Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Response To UV-A Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Process Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Response To Epidermal Growth Factor Stimulus Mitotic Cell Cycle Response To Epidermal Growth Factor Homeostasis Of Number Of Cells Positive Regulation Of Vasoconstriction Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Glycogen Biosynthetic Process Regulation Of Nitric-oxide Synthase Activity Regulation Of Glycogen Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Cell Cycle Process Regulation Of Vasoconstriction Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Glucose Import Cellular Response To Mechanical Stimulus Cell Cycle Regulation Of Generation Of Precursor Metabolites And Energy Cellular Response To Organonitrogen Compound Homeostatic Process Regulation Of Oxidoreductase Activity Embryonic Organ Development Gland Development In Utero Embryonic Development Positive Regulation Of Reactive Oxygen Species Metabolic Process Cell Surface Receptor Signaling Pathway Alkanesulfonate Metabolic Process Glycogen Cell Differentiation Involved In Embryonic Placenta Development Regulation Of Glucose Transport Glial Cell Development Cellular Response To Hormone Stimulus Regulation Of Glucose Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Reactive Oxygen Species Metabolic Process Embryonic Placenta Development Cell Activation Response To UV Cellular Response To Stimulus Digestive Tract Development Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling
Tagcloud ?		adapter binds bps cooperatively designated detectable dissociates domains fragment grb10 homologous homology hybrid interacting leaving links modulates motifs phosphotyrosine presumably proline tagged tandem terminus transfection transiently
Tagcloud (Difference) ?		adapter binds bps cooperatively designated detectable dissociates domains fragment grb10 homologous homology hybrid interacting leaving links modulates motifs phosphotyrosine presumably proline tagged tandem terminus transfection transiently
Tagcloud (Intersection) ?