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PDCD6IP and TNIP2
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
PDCD6IP
TNIP2
Gene Name
programmed cell death 6 interacting protein
TNFAIP3 interacting protein 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Immunological Synapse
Cytoplasm
Microtubule Organizing Center
Cytosol
Focal Adhesion
Membrane
Vesicle
Melanosome
Extracellular Vesicular Exosome
Endoplasmic Reticulum Exit Site
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
Protein Binding
SH3 Domain Binding
Proteinase Activated Receptor Binding
Protein Homodimerization Activity
Calcium-dependent Protein Binding
Protein Binding
Protein Kinase Binding
Polyubiquitin Binding
Biological Process
Cell Separation After Cytokinesis
Apoptotic Process
Nucleus Organization
Mitotic Metaphase Plate Congression
Regulation Of Centrosome Duplication
Protein Transport
Viral Process
Viral Life Cycle
Viral Budding Via Host ESCRT Complex
Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Regulation Of Mitotic Spindle Assembly
Positive Regulation Of Exosomal Secretion
Regulation Of Extracellular Vesicular Exosome Assembly
Positive Regulation Of Extracellular Vesicular Exosome Assembly
Transcription, DNA-templated
Apoptotic Process
Inflammatory Response
I-kappaB Kinase/NF-kappaB Signaling
CD40 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Positive Regulation Of Macrophage Activation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein Stabilization
Positive Regulation Of B Cell Activation
Interleukin-1-mediated Signaling Pathway
Cellular Response To Lipopolysaccharide
Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways
HIV Life Cycle
Budding and maturation of HIV virion
Uptake and actions of bacterial toxins
HIV Infection
Uptake and function of anthrax toxins
Late Phase of HIV Life Cycle
Signaling by Interleukins
Cytokine Signaling in Immune system
Interleukin-1 signaling
Drugs
Diseases
GWAS
Visceral adipose tissue adjusted for BMI (
22589738
)
Protein-Protein Interactions
35 interactors:
ARRDC1
ARRDC3
ATN1
CD2AP
CEP55
CHMP4A
CHMP4B
CHMP4C
CXCR1
EGFR
F2R
GRB2
HOXA1
ITSN1
ITSN2
KEAP1
MAPK6
PDCD6
PTK2B
RAMP3
RNF11
SDCBP
SH3GL1
SH3GL2
SH3GL3
SH3KBP1
SH3RF1
SRC
TAB1
TNIP2
TSG101
TTF2
VPS28
VPS37C
YES1
23 interactors:
APP
CDKN1A
CHUK
EP300
FBXO25
FLNA
IKBKG
MAP3K8
MAPK1
MKNK1
NCOR2
NFKB1
NFKB2
PDCD6IP
PSMD9
REL
RELA
SMARCD1
SRPK2
STK11
TEK
TNFAIP3
UBC
Entrez ID
10015
79155
HPRD ID
06425
18207
Ensembl ID
ENSG00000170248
ENSG00000168884
Uniprot IDs
C5MQH7
Q8WUM4
D6RGJ2
Q8NFZ5
PDB IDs
2OEV
2OEW
2OEX
2OJQ
2R02
2R03
2R05
2XS1
2XS8
2ZNE
3C3O
3C3Q
3C3R
3E1R
4JJY
Enriched GO Terms of Interacting Partners
?
Virion Assembly
Locomotion
Endocytosis
Vesicle-mediated Transport
Movement Of Cell Or Subcellular Component
Cell Migration
Cell Separation After Cytokinesis
Membrane Organization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Cell Motility
Axon Guidance
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Chemotaxis
Viral Budding
Transport
Regulation Of Signal Transduction
Viral Life Cycle
Regulation Of Cellular Process
Establishment Of Protein Localization
Endosomal Transport
Viral Protein Processing
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Axonogenesis
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of ERBB Signaling Pathway
Cellular Response To Organic Substance
Positive Regulation Of Signal Transduction
Viral Process
Axon Development
Regulation Of Signaling
Cell Morphogenesis Involved In Neuron Differentiation
Neuron Projection Development
Regulation Of MAPK Cascade
Neuron Projection Morphogenesis
Regulation Of Intracellular Signal Transduction
Cell Projection Organization
Response To Organic Substance
Multicellular Organismal Development
Regulation Of Organelle Organization
Response To External Stimulus
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Vacuolar Transport
Positive Regulation Of Metabolic Process
Intracellular Transport
Neuron Development
Anatomical Structure Development
Apoptotic Process
Cell Morphogenesis Involved In Differentiation
Intracellular Signal Transduction
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Innate Immune Response
Regulation Of Type I Interferon Production
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Immune System Process
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
MyD88-dependent Toll-like Receptor Signaling Pathway
Apoptotic Process
Activation Of Innate Immune Response
Positive Regulation Of Type I Interferon Production
Toll-like Receptor 4 Signaling Pathway
Programmed Cell Death
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Cell Death
Death
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Innate Immune Response
Immune Response-regulating Signaling Pathway
Positive Regulation Of Immune System Process
Toll-like Receptor Signaling Pathway
T Cell Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Response To Stress
I-kappaB Kinase/NF-kappaB Signaling
Immune Response
Positive Regulation Of Cytokine Production
Regulation Of Cytokine Production
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Defense Response
Antigen Receptor-mediated Signaling Pathway
Regulation Of Innate Immune Response
Signal Transduction
Regulation Of Immune Response
Positive Regulation Of Immune Response
Positive Regulation Of Gene Expression
NIK/NF-kappaB Signaling
Positive Regulation Of Protein Metabolic Process
Signaling
Positive Regulation Of Cellular Biosynthetic Process
Tagcloud
?
129n
146n
adjuvanted
arepanrix
batch
batches
deamidation
dige
dioxidation
fabp
focetria
gallus
glycosylation
h1n1
ha1
ha2
hemagglutinin
latticed
ma1
manufacturing
narcolepsy
neuraminidase
nucleoprotein
pandemrix
ph1n1
sulfation
tspan8
tub
vaccines
Tagcloud (Difference)
?
129n
146n
adjuvanted
arepanrix
batch
batches
deamidation
dige
dioxidation
fabp
focetria
gallus
glycosylation
h1n1
ha1
ha2
hemagglutinin
latticed
ma1
manufacturing
narcolepsy
neuraminidase
nucleoprotein
pandemrix
ph1n1
sulfation
tspan8
tub
vaccines
Tagcloud (Intersection)
?