| Novel |
MARCHF2
|
membrane associated ring-CH-type finger 2 |
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| Novel |
SHFL
|
shiftless antiviral inhibitor of ribosomal frameshifting |
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| Novel |
ZNF44
|
zinc finger protein 44 |
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| Novel |
ZNF562
|
zinc finger protein 562 |
- Generic Transcription Pathway
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| Novel |
ZNF823
|
zinc finger protein 823 |
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A2M
|
alpha-2-macroglobulin |
- Platelet degranulation
- Intrinsic Pathway of Fibrin Clot Formation
- Degradation of the extracellular matrix
- HDL assembly
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- Becaplermin
- Cisplatin
- Bacitracin
- Zinc
- Ocriplasmin
- Silver
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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ALDH3A1
|
aldehyde dehydrogenase 3 family member A1 |
- Phase I - Functionalization of compounds
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APOE
|
apolipoprotein E |
- Nuclear signaling by ERBB4
- Scavenging by Class A Receptors
- Scavenging by Class A Receptors
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
- Post-translational protein phosphorylation
- Chylomicron assembly
- Chylomicron remodeling
- Chylomicron clearance
- Chylomicron clearance
- HDL remodeling
- NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
- Retinoid metabolism and transport
- Retinoid metabolism and transport
- Amyloid fiber formation
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- Zinc
- Copper
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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- Alzheimer's disease (AD)
- Hyperlipoproteinemia, type III; Dysbetalipoproteinemia
- Lipoprotein glomerulopathy
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CDC37
|
cell division cycle 37, HSP90 cochaperone |
- Signaling by ERBB2
- Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
- Constitutive Signaling by EGFRvIII
- Regulation of necroptotic cell death
- Downregulation of ERBB2 signaling
- RHOBTB2 GTPase cycle
- Constitutive Signaling by Overexpressed ERBB2
- Drug-mediated inhibition of ERBB2 signaling
- Signaling by ERBB2 KD Mutants
- Resistance of ERBB2 KD mutants to trastuzumab
- Resistance of ERBB2 KD mutants to sapitinib
- Resistance of ERBB2 KD mutants to tesevatinib
- Resistance of ERBB2 KD mutants to neratinib
- Resistance of ERBB2 KD mutants to osimertinib
- Resistance of ERBB2 KD mutants to afatinib
- Resistance of ERBB2 KD mutants to AEE788
- Resistance of ERBB2 KD mutants to lapatinib
- Signaling by ERBB2 ECD mutants
- Signaling by ERBB2 TMD/JMD mutants
- Drug resistance in ERBB2 TMD/JMD mutants
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CDKN1C
|
cyclin dependent kinase inhibitor 1C |
- Cyclin D associated events in G1
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
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- Beckwith-Wiedemann syndrome
- Adrenal carcinoma
|
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DOCK8
|
dedicator of cytokinesis 8 |
- CDC42 GTPase cycle
- RAC1 GTPase cycle
- RHOJ GTPase cycle
- Factors involved in megakaryocyte development and platelet production
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- Non-syndromic autosomal dominant mental retardation
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ECSIT
|
ECSIT signaling integrator |
- MyD88:MAL(TIRAP) cascade initiated on plasma membrane
- Complex I biogenesis
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
- MyD88 cascade initiated on plasma membrane
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FBF1
|
Fas binding factor 1 |
- Anchoring of the basal body to the plasma membrane
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FXYD3
|
FXYD domain containing ion transport regulator 3 |
- Ion homeostasis
- Ion transport by P-type ATPases
- Potential therapeutics for SARS
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GEMIN4
|
gem nuclear organelle associated protein 4 |
- snRNP Assembly
- SARS-CoV-2 modulates host translation machinery
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LNX1
|
ligand of numb-protein X 1 |
- Antigen processing: Ubiquitination & Proteasome degradation
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MAST1
|
microtubule associated serine/threonine kinase 1 |
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PSEN1
|
presenilin 1 |
- Nuclear signaling by ERBB4
- Degradation of the extracellular matrix
- Regulated proteolysis of p75NTR
- NRIF signals cell death from the nucleus
- Activated NOTCH1 Transmits Signal to the Nucleus
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- NOTCH2 Activation and Transmission of Signal to the Nucleus
- EPH-ephrin mediated repulsion of cells
- Neutrophil degranulation
- NOTCH3 Activation and Transmission of Signal to the Nucleus
- NOTCH4 Activation and Transmission of Signal to the Nucleus
- Noncanonical activation of NOTCH3
- TGFBR3 PTM regulation
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- Alzheimer's disease (AD)
- Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3)
- Acne inversa; Hidradenitis supprativa
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PSEN2
|
presenilin 2 |
- Nuclear signaling by ERBB4
- Regulated proteolysis of p75NTR
- NRIF signals cell death from the nucleus
- Activated NOTCH1 Transmits Signal to the Nucleus
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- NOTCH2 Activation and Transmission of Signal to the Nucleus
- EPH-ephrin mediated repulsion of cells
- NOTCH3 Activation and Transmission of Signal to the Nucleus
- NOTCH4 Activation and Transmission of Signal to the Nucleus
- Noncanonical activation of NOTCH3
- TGFBR3 PTM regulation
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PSME3
|
proteasome activator subunit 3 |
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