SENP8 and USP15

  • Number of citations of the paper that reports this interaction (PMID 22626734)
  • 2
  • Data Source:
  • BioGRID (enzymatic study)

SENP8

USP15

Gene Name SUMO/sentrin specific peptidase family member 8 ubiquitin specific peptidase 15
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Metabolite levels (HVA/MHPG ratio) ( 23319000)
  • Pulmonary function decline ( 22424883)
Protein-Protein Interactions 12 interactors: COPS2 CUL1 CUL2 CUL4A GPS1 NEDD8 PLA2G2A SMURF1 UBB USP15 USP21 USP28 45 interactors: BAP1 BMPR1A BRAP CARD9 CCDC57 FHL1 HIST2H2BE JOSD1 MAD1L1 OTUB1 PHF7 PLA2G2A RBCK1 RNF126 RNF144B SART3 SENP3 SENP8 SMAD3 SPDL1 STAM STK33 TRAF6 TRIM17 TRIM21 TRIM25 TRIM46 TRIM5 TRIM54 TRIM63 TRIM74 UBC UBE2S UCHL1 UCHL3 USP14 USP20 USP21 USP28 USP33 USP4 USP51 USP7 USP8 YOD1
Entrez ID 123228 9958
HPRD ID 09784 05293
Ensembl ID ENSG00000166192 ENSG00000135655
Uniprot IDs A8K8D3 Q96LD8 Q9Y4E8
PDB IDs 1XT9 2BKQ 2BKR 1W6V 3LMN 3PPA 3PV1 3T9L 4A3O 4A3P
Enriched GO Terms of Interacting Partners?
Tagcloud ?
attributed  bca3  bind  conversely  crucial  cullins  deacetylase  du145  link  mcf7  modification  nad  necrosis  nedd8  neddylated  neddylation  nfkappab  p65  prolongs  protease  recruit  reversed  silencing  sirt1  span  substrates  ubiquitin  worms  yeast 
antitumor  bacterial  boost  challenge  characterized  class  crucial  deficiency  degradation  deubiquitinases  dub  dubs  e3  enhanced  induce  ligase  mdm2  negatively  nfatc2  physiological  promoted  regulated  regulator  responses  stabilized  targeting  targets  turn  ubiquitin 
Tagcloud (Difference) ?
attributed  bca3  bind  conversely  cullins  deacetylase  du145  link  mcf7  modification  nad  necrosis  nedd8  neddylated  neddylation  nfkappab  p65  prolongs  protease  recruit  reversed  silencing  sirt1  span  substrates  worms  yeast 
antitumor  bacterial  boost  challenge  characterized  class  deficiency  degradation  deubiquitinases  dub  dubs  e3  enhanced  induce  ligase  mdm2  negatively  nfatc2  physiological  promoted  regulated  regulator  responses  stabilized  targeting  targets  turn 
Tagcloud (Intersection) ?
crucial  ubiquitin