SENP8 and NEDD8

  • Number of citations of the paper that reports this interaction (PMID 15775960)
  • 28
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vitro)

SENP8

NEDD8

Gene Name SUMO/sentrin specific peptidase family member 8 neural precursor cell expressed, developmentally down-regulated 8
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Metabolite levels (HVA/MHPG ratio) ( 23319000)
Protein-Protein Interactions 12 interactors: COPS2 CUL1 CUL2 CUL4A GPS1 NEDD8 PLA2G2A SMURF1 UBB USP15 USP21 USP28 34 interactors: AHR ANK1 ARIH1 ARIH2 CDC34 COPS5 COPS6 CTRC CUL1 CUL2 CUL3 CUL4B CUL5 DCUN1D1 DNMT3B NAE1 NPLOC4 NUB1 PARP1 PSMD4 PTK2 RPL11 SENP8 SMURF1 TP53 UBA2 UBA3 UBE2F UBE2K UBE2M UBXN7 UCHL1 UCHL3 UFD1L
Entrez ID 123228 4738
HPRD ID 09784 04412
Ensembl ID ENSG00000166192 ENSG00000129559
Uniprot IDs A8K8D3 Q96LD8 Q15843
PDB IDs 1XT9 2BKQ 2BKR 1NDD 1R4M 1R4N 1XT9 2BKR 2KO3 2NVU 3DBH 3DBL 3DBR 3DQV 3GZN 4F8C 4FBJ 4HCP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
attributed  bca3  bind  conversely  crucial  cullins  deacetylase  du145  link  mcf7  modification  nad  necrosis  nedd8  neddylated  neddylation  nfkappab  p65  prolongs  protease  recruit  reversed  silencing  sirt1  span  substrates  ubiquitin  worms  yeast 
activate  activates  activating  analyze  app  appbp1  covalently  cullin  discuss  downregulates  driven  existing  gradual  gradually  hypothesize  insights  integrity  investigation  ligases  lost  modifies  neddylation  precursor  protects  reverse  slow  switches  turnover  ubiquitin 
Tagcloud (Difference) ?
attributed  bca3  bind  conversely  crucial  cullins  deacetylase  du145  link  mcf7  modification  nad  necrosis  neddylated  nfkappab  p65  prolongs  protease  recruit  reversed  silencing  sirt1  span  substrates  worms  yeast 
activate  activates  activating  analyze  app  appbp1  covalently  cullin  discuss  downregulates  driven  existing  gradual  gradually  hypothesize  insights  integrity  investigation  ligases  lost  modifies  precursor  protects  reverse  slow  switches  turnover 
Tagcloud (Intersection) ?
nedd8  neddylation  ubiquitin