FAM193B and PKN2

  • Number of citations: 0 (PubMedID 21900206)
  • Data Source: BioGRID (two hybrid)

FAM193B

PKN2

Name family with sequence similarity 193 member B protein kinase N2
Structure No pdb structure PDB 4CRS
GO Annotations Cellular Component
Molecular Function
Biological Process None
Pathways None
Drugs None
GWAS
  • Appendicular lean mass ( 33097823 )
  • L1-L4 bone mineral density x serum urate levels interaction ( 34046847 )
  • Waist-to-hip ratio adjusted for BMI ( 26426971 )
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971 )
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )
  • Age at first sexual intercourse ( 34211149 )
  • Alanine aminotransferase levels ( 34315874 33547301 )
  • Appendicular lean mass ( 33097823 )
  • Aspartate aminotransferase levels ( 34315874 33547301 )
  • Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143 )
  • Coronary artery disease ( 29212778 )
  • Diastolic blood pressure ( 27841878 )
  • General risk tolerance (MTAG) ( 30643258 )
  • Heel bone mineral density ( 28869591 30598549 )
  • Height ( 25282103 31562340 20881960 )
  • Intraocular pressure ( 29617998 )
  • Liver enzyme levels (alanine transaminase) ( 33972514 )
  • Liver enzyme levels (gamma-glutamyl transferase) ( 22001757 33972514 )
  • Narcolepsy ( 23459209 )
  • Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095 )
  • Paclitaxel disposition in epithelial ovarian cancer ( 29367611 )
  • Periodontal microbiota ( 22699663 )
  • Photic sneeze reflex ( 27182965 )
  • Pulse pressure ( 27841878 )
  • Red blood cell count ( 32888494 )
  • Refractive error ( 32231278 )
  • Response to fenofibrate (LDL cholesterol levels) ( 27002377 )
  • Rosacea symptom severity ( 29771307 )
  • Serum protein levels (sST2) ( 23999434 )
  • Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306 )
  • Systolic blood pressure ( 27841878 30224653 )
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993 )
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993 )
  • Waist circumference adjusted for body mass index ( 34021172 )
  • White matter hyperintensity volume ( 33293549 )
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549 )
Novel Interactors None recorded 1 novel interactors: PTBP2
Interacting Genes 12 interacting genes: ATXN1 CDC25A CNOT11 GOLGA2 GSK3A GSK3B LDOC1 MAPK8 PKN2 SPANXN2 TRIM23 TRIM27 19 interacting genes: AKT1 CASP3 CCDC136 CHGB EEF1A1 EIF3G FAM193B HDAC5 MAP3K2 MYO9B NCK1 NCK2 NEDD4 PDPK1 PLCG1 PTPN13 RHOA RNF10 SUMO2
Entrez ID 54540 5586
HPRD ID 07671 03972
Ensembl ID ENSG00000146067 ENSG00000065243
Uniprot IDs Q96PV7 Q16513
PDB IDs Not available 4CRS 4RRV 6CCY 6GBE
GO Terms Enriched among Interactors