SGSM2 and PNO1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		SGSM2	PNO1
Description		small G protein signaling modulator 2	partner of NOB1 homolog
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoplasmic Vesicle Melanosome	Nucleus Nucleoplasm Nucleolus Cytosol Small-subunit Processome
	Molecular Function	GTPase Activator Activity Small GTPase Binding	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Late Endosome To Golgi Transport	Ribosomal Small Subunit Biogenesis
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Aortic root size ( 19584346) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fasting blood proinsulin levels ( 23263489) Household income (MTAG) ( 31844048) Insulin-related traits (multivariate analysis) ( 32002517) Multiple sclerosis ( 31604244) Number of sexual partners ( 30643258) Proinsulin levels ( 21873549) Schizophrenia ( 25056061)
Interacting Genes		21 interacting genes: AFP CA12 CELSR3 CHD3 DSCR9 EGFR FNBP1L GDPD2 ILF2 KHDRBS3 MPP1 MTDH PNO1 PTN RAB2A RAB2B RAB3A RAB3B RAB9B RGMA RPS25	10 interacting genes: ATP5F1C FRZB GSTP1 IGFBP5 KLF6 PDPK1 PICK1 RXRG SGSM2 SUPT5H
Entrez ID		9905	56902
HPRD ID		15284	14250
Ensembl ID		ENSG00000141258	ENSG00000115946
Uniprot IDs		B9A6J3 O43147	Q9NRX1
PDB IDs			6G18 6G4S 6G4W 6G51 6G53 6G5I 6ZUO 6ZXD 6ZXE 7MQ8 7MQ9 7MQA 7WTS 7WTT 7WTU 7WTV 7WTW 7WTX 7WTZ 7WU0 8ZDC 8ZDD
Enriched GO Terms of Interacting Partners?		Estrous Cycle GTPase Activity GTP Binding GDP Binding Myosin V Binding Ovulation Cycle Acrosomal Vesicle GTP-dependent Protein Binding Regulation Of Axon Regeneration	Cellular Developmental Process Negative Regulation Of Hepatocyte Differentiation Negative Regulation Of Growth Cell Development Cellular Response To Epidermal Growth Factor Stimulus Negative Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Smooth Muscle Cell Proliferation Dinitrosyl-iron Complex Binding S-nitrosoglutathione Binding Response To Epidermal Growth Factor Nitric Oxide Storage Negative Regulation Of Muscle Hypertrophy Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Skeletal Muscle Hypertrophy 3-phosphoinositide-dependent Protein Kinase Activity Glial Cell Development Regulation Of Cartilage Development Regulation Of Smooth Muscle Cell Migration Response To Peptide Hormone Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion TRAF2-GSTP1 Complex DSIF Complex Negative Regulation Of Cell Communication Negative Regulation Of Signaling Cellular Response To Insulin Stimulus Regulation Of Cell Growth Insulin-like Growth Factor Binding Protein Complex Regulation Of Cell Population Proliferation Regulation Of Cell Migration Glutathione Derivative Biosynthetic Process Cellular Response To Cell-matrix Adhesion Insulin-like Growth Factor Ternary Complex Membrane Curvature Sensor Activity Epithelial Cell Development Convergent Extension Involved In Organogenesis Regulation Of Cell Motility Negative Regulation Of Smooth Muscle Cell Chemotaxis Nitric Oxide Binding Response To L-ascorbic Acid Mammary Gland Involution Positive Regulation Of Sarcomere Organization
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