SGSM2 and GDPD2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SGSM2	GDPD2
Description		small G protein signaling modulator 2	glycerophosphodiester phosphodiesterase domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoplasmic Vesicle Melanosome	Cytoplasm Cytoskeleton Actin Filament Plasma Membrane Membrane Lamellipodium
	Molecular Function	GTPase Activator Activity Small GTPase Binding	Phosphoric Diester Hydrolase Activity Glycerophosphodiester Phosphodiesterase Activity Hydrolase Activity Metal Ion Binding Glycerophosphoinositol Inositolphosphodiesterase Activity
	Biological Process	Late Endosome To Golgi Transport	Lipid Metabolic Process Actin Filament Organization Positive Regulation Of Osteoblast Differentiation
Pathways
Drugs
Diseases
GWAS		Aortic root size ( 19584346) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fasting blood proinsulin levels ( 23263489) Household income (MTAG) ( 31844048) Insulin-related traits (multivariate analysis) ( 32002517) Multiple sclerosis ( 31604244) Number of sexual partners ( 30643258) Proinsulin levels ( 21873549) Schizophrenia ( 25056061)
Interacting Genes		21 interacting genes: AFP CA12 CELSR3 CHD3 DSCR9 EGFR FNBP1L GDPD2 ILF2 KHDRBS3 MPP1 MTDH PNO1 PTN RAB2A RAB2B RAB3A RAB3B RAB9B RGMA RPS25	5 interacting genes: ATP5F1C DRD2 FRA10AC1 HEXD SGSM2
Entrez ID		9905	54857
HPRD ID		15284	06528
Ensembl ID		ENSG00000141258	ENSG00000130055
Uniprot IDs		B9A6J3 O43147	Q9HCC8
PDB IDs
Enriched GO Terms of Interacting Partners?		Estrous Cycle GTPase Activity GTP Binding GDP Binding Myosin V Binding Ovulation Cycle Acrosomal Vesicle GTP-dependent Protein Binding Regulation Of Axon Regeneration	Proton-transporting ATP Synthase Activity, Rotational Mechanism Negative Regulation Of Synaptic Transmission, Glutamatergic Auditory Behavior Cellular Response To Ethanol Response To Histamine Regulation Of Synapse Structural Plasticity Anatomical Structure Regression Dopamine Binding Regulation Of Renal Sodium Excretion Dopamine Neurotransmitter Receptor Activity Regulation Of Synapse Organization Cerebral Cortex GABAergic Interneuron Migration Negative Regulation Of Cellular Response To Hypoxia Regulation Of Developmental Growth Neurotransmitter Transport Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Dopamine Receptor Signaling Pathway Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway G Protein-coupled Receptor Complex Catecholamine Uptake Dopamine Uptake Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Adenohypophysis Development Negative Regulation Of Dephosphorylation Response To Inactivity Positive Regulation Of Renal Sodium Excretion Interneuron Migration Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Negative Regulation Of Neuron Migration Negative Regulation Of Circadian Rhythm Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Grooming Behavior Hyaloid Vascular Plexus Regression Regulation Of Growth Hormone Secretion Dopaminergic Synapse Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Prepulse Inhibition Neuron-neuron Synaptic Transmission Interneuron Migration From The Subpallium To The Cortex Branching Morphogenesis Of A Nerve Negative Regulation Of Dopamine Secretion Peristalsis Striatum Development Positive Regulation Of Growth Hormone Secretion Positive Regulation Of Neurotransmitter Uptake Regulation Of Dopamine Uptake Involved In Synaptic Transmission G Protein-coupled Receptor Internalization Heterotrimeric G-protein Binding
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