SGSM2 and CA12

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SGSM2	CA12
Description		small G protein signaling modulator 2	carbonic anhydrase 12
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoplasmic Vesicle Melanosome	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	GTPase Activator Activity Small GTPase Binding	Carbonate Dehydratase Activity Zinc Ion Binding Lyase Activity Metal Ion Binding
	Biological Process	Late Endosome To Golgi Transport	Estrous Cycle Chloride Ion Homeostasis
Pathways			Reversible hydration of carbon dioxide
Drugs			Benzthiazide Hydroflumethiazide Acetazolamide Zonisamide Ellagic acid
Diseases
GWAS		Aortic root size ( 19584346) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fasting blood proinsulin levels ( 23263489) Household income (MTAG) ( 31844048) Insulin-related traits (multivariate analysis) ( 32002517) Multiple sclerosis ( 31604244) Number of sexual partners ( 30643258) Proinsulin levels ( 21873549) Schizophrenia ( 25056061)	Daytime nap ( 33568662) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Refractive error ( 32231278)
Interacting Genes		21 interacting genes: AFP CA12 CELSR3 CHD3 DSCR9 EGFR FNBP1L GDPD2 ILF2 KHDRBS3 MPP1 MTDH PNO1 PTN RAB2A RAB2B RAB3A RAB3B RAB9B RGMA RPS25	10 interacting genes: ATP5F1C CUX1 DAXX KATNBL1 LGALS7 MAPK6 MRPL9 RDH11 SGSM2 TOE1
Entrez ID		9905	771
HPRD ID		15284	04464
Ensembl ID		ENSG00000141258	ENSG00000074410
Uniprot IDs		B9A6J3 O43147	B3KUB4 O43570
PDB IDs			1JCZ 1JD0 4HT2 4KP5 4KP8 4Q0L 4QJ0 4QJO 4QJW 4WW8 5LL5 5LL9 5LLO 5LLP 5MSA 5MSB 6G5L 6G7A 6QN0 6QNG 6QNL 6R6Y 6R71 6RPS 6T5P 6T5Q 7PP9 7PUU 7PUV 7PUW 8CO3
Enriched GO Terms of Interacting Partners?		Estrous Cycle GTPase Activity GTP Binding GDP Binding Myosin V Binding Ovulation Cycle Acrosomal Vesicle GTP-dependent Protein Binding Regulation Of Axon Regeneration
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