Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
SRGAP3 and WASF1
Number of citations of the paper that reports this interaction (PMID
12447388
)
46
Data Source:
HPRD
(in vivo, in vitro)
SRGAP3
WASF1
Gene Name
SLIT-ROBO Rho GTPase activating protein 3
WAS protein family, member 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Cytoskeleton
Actin Cytoskeleton
Cell Junction
SCAR Complex
Synapse
Molecular Function
Protein Binding
Rac GTPase Activator Activity
Rac GTPase Binding
Actin Binding
Protein Binding
Protein Complex Binding
Rac GTPase Binding
Biological Process
Small GTPase Mediated Signal Transduction
Negative Regulation Of Cell Migration
Positive Regulation Of Rac GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Protein Complex Assembly
Movement Of Cell Or Subcellular Component
Rac Protein Signal Transduction
Actin Filament Polymerization
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Inactivation of Cdc42 and Rac
Rho GTPase cycle
Axon guidance
Signaling by Rho GTPases
Signaling by Robo receptor
Signaling by VEGF
Fcgamma receptor (FCGR) dependent phagocytosis
VEGFA-VEGFR2 Pathway
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
9 interactors:
DISC1
DTNBP1
FASLG
KDM1A
PRMT6
SMARCC2
SUV39H1
TNIK
WASF1
28 interactors:
ABI1
ABL1
ACTB
ACTG1
ACTR2
BAD
BAIAP2
BRK1
CDC42
CDK5
CRK
CXCL8
CYFIP2
DNMBP
FYN
GNAI1
GRB2
IFT20
IL12A
NCK1
NCKAP1
PFN1
PRKAR2A
PSTPIP1
RAC1
SORBS2
SRGAP3
TRIP10
Entrez ID
9901
8936
HPRD ID
12108
05434
Ensembl ID
ENSG00000196220
ENSG00000112290
Uniprot IDs
O43295
Q92558
PDB IDs
3P8C
Enriched GO Terms of Interacting Partners
?
Organelle Organization
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Cell Differentiation
Chromatin Modification
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Chromatin Organization
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Neural Precursor Cell Proliferation
Actin Cytoskeleton Reorganization
Positive Regulation Of Stem Cell Proliferation
Histone Modification
Chromosome Organization
Regulation Of Primitive Erythrocyte Differentiation
Endomembrane System Organization
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Forebrain Development
Cytoskeleton Organization
Regulation Of Metabolic Process
Regulation Of Neural Precursor Cell Proliferation
Nervous System Development
Histone H3-R2 Methylation
Transcription, DNA-templated
Developmental Process
Regulation Of Stem Cell Proliferation
RNA Biosynthetic Process
Histone Methylation
Endosomal Lumen Acidification
Actin Cytoskeleton Organization
Response To Stimulus
Positive Regulation Of Cellular Metabolic Process
Actin Filament-based Process
Retinal Cell Programmed Cell Death
System Development
Generation Of Neurons
Regulation Of Signal Transduction
Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment
Protein Methylation
Regulation Of Cellular Process
Necroptotic Signaling Pathway
Neurogenesis
Brain Development
Histone H3-K9 Dimethylation
Regulation Of Dopamine Receptor Signaling Pathway
Head Development
Negative Regulation Of Histone H3-K4 Methylation
Histone H3-K9 Demethylation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc Receptor Signaling Pathway
Endocytosis
Phagocytosis
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Vesicle-mediated Transport
Innate Immune Response
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Immune Response
Defense Response
Positive Regulation Of Immune System Process
Positive Regulation Of Immune Response
Regulation Of Immune Response
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Immune System Process
Actin Cytoskeleton Organization
Actin Filament-based Process
Immune System Process
Response To Stress
Signaling
Blood Coagulation
Cell Communication
Hemostasis
Movement Of Cell Or Subcellular Component
Signal Transduction
Regulation Of Actin Cytoskeleton Organization
Regulation Of Cytoskeleton Organization
Cell Surface Receptor Signaling Pathway
Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Transport
Cellular Response To Stimulus
Regulation Of Body Fluid Levels
Locomotion
Wound Healing
Cell Projection Morphogenesis
Cell Part Morphogenesis
Cytoskeleton Organization
Cell Projection Organization
Response To Stimulus
Response To Wounding
Axonogenesis
Axon Guidance
Ephrin Receptor Signaling Pathway
Axon Development
Tagcloud
?
3p
anomalies
arm
camk1
congenital
creld1
define
deleted
deletion
deletions
features
give
handicap
interstitial
involve
kb
lengths
mb
mtmr14
overlap
presents
prove
respect
rise
seizures
syndrome
tada3
terminus
typical
Tagcloud (Difference)
?
3p
anomalies
arm
camk1
congenital
creld1
define
deleted
deletion
deletions
features
give
handicap
interstitial
involve
kb
lengths
mb
mtmr14
overlap
presents
prove
respect
rise
seizures
syndrome
tada3
terminus
typical
Tagcloud (Intersection)
?