SRGAP3

Gene Name		SLIT-ROBO Rho GTPase activating protein 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Protein Binding Rac GTPase Activator Activity Rac GTPase Binding
	Biological Process	Small GTPase Mediated Signal Transduction Negative Regulation Of Cell Migration Positive Regulation Of Rac GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Inactivation of Cdc42 and Rac Rho GTPase cycle Axon guidance Signaling by Rho GTPases Signaling by Robo receptor
Drugs
Diseases
GWAS
Protein-protein Interactions		9 interactors: DISC1 DTNBP1 FASLG KDM1A PRMT6 SMARCC2 SUV39H1 TNIK WASF1
Entrez ID		9901
HPRD ID		12108
Ensembl ID		ENSG00000196220
Uniprot IDs		O43295
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cell Differentiation Chromatin Modification Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Chromatin Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Neural Precursor Cell Proliferation Actin Cytoskeleton Reorganization Positive Regulation Of Stem Cell Proliferation Histone Modification Chromosome Organization Regulation Of Primitive Erythrocyte Differentiation Endomembrane System Organization Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Forebrain Development Cytoskeleton Organization Regulation Of Metabolic Process Regulation Of Neural Precursor Cell Proliferation Nervous System Development Histone H3-R2 Methylation Transcription, DNA-templated Developmental Process Regulation Of Stem Cell Proliferation RNA Biosynthetic Process Histone Methylation Endosomal Lumen Acidification Actin Cytoskeleton Organization Response To Stimulus Positive Regulation Of Cellular Metabolic Process Actin Filament-based Process Retinal Cell Programmed Cell Death System Development Generation Of Neurons Regulation Of Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Protein Methylation Regulation Of Cellular Process Necroptotic Signaling Pathway Neurogenesis Brain Development Histone H3-K9 Dimethylation Regulation Of Dopamine Receptor Signaling Pathway Head Development Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation
Tagcloud ?		3p anomalies arm camk1 congenital creld1 define deleted deletion deletions features give handicap interstitial involve kb lengths mb mtmr14 overlap presents prove respect rise seizures syndrome tada3 terminus typical