MED24 and CTDP1

Number of citations of the paper that reports this interaction (PubMedID 16239144)
0

Data Source:
BioGRID (pull down)

		MED24	CTDP1
Description		mediator complex subunit 24	CTD phosphatase subunit 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mediator Complex Core Mediator Complex	Spindle Pole Nucleus Nucleoplasm Cytoplasm Centrosome Spindle Cytoskeleton Midbody Protein-containing Complex Spindle Midzone
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Nuclear Vitamin D Receptor Binding Nuclear Thyroid Hormone Receptor Binding	TFIIF-class Transcription Factor Complex Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Hydrolase Activity Tat Protein Binding
	Biological Process	Transcription By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II Somatic Stem Cell Population Maintenance Positive Regulation Of DNA-templated Transcription RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Protein Dephosphorylation Exit From Mitosis Host-mediated Activation Of Viral Transcription Cell Division Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Asthma ( 31619474) Bipolar disorder ( 31043756) Eosinophil count ( 32888494) Estimated glomerular filtration rate ( 31152163) Mitochondrial DNA copy number ( 30704525) Neutrophil count ( 25096241 29403010) Neutrophil percentage of white cells ( 32888494) Pancreatic ductal adenocarcinoma ( 30541042) Pursuit maintenance gain ( 29064472) Refractive error ( 32231278) White blood cell count ( 20139978 21738480 22037903 28158719 32888494)	Adverse response to drug ( 30420678) Cerebrospinal P-tau181p levels ( 28247064) Metabolite levels ( 23823483) Monocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 32888494) Schizophrenia ( 23212062) Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes		15 interacting genes: APP AR CEBPA CTDP1 ESR1 ESR2 GSK3B HNF4A MED9 PPARA PPARG RPS6KA6 RXRA SREBF1 TNFSF11	41 interacting genes: AKT1 CDK7 CDK8 CDK9 CSNK2A1 CSNK2A2 CSNK2B E2F1 ELP2 ELP3 ERH GTF2F1 INTS1 INTS3 INTS6 INTS7 INTS8 MED1 MED15 MED16 MED17 MED23 MED24 MED25 MED26 MED4 MED6 MED7 MED8 NDRG2 POLR2A POLR2B PRKDC PRMT5 SNRNP70 SNRPB STK38 TCEA1 UPP1 USP7 WDR77
Entrez ID		9862	9150
HPRD ID		06107	05377
Ensembl ID		ENSG00000008838	ENSG00000060069
Uniprot IDs		F5GY88 O75448	Q9Y5B0
PDB IDs		7EMF 7ENA 7ENC 7ENJ 7LBM 8GXQ 8GXS 8T9D 8TQW 8TRH	1J2X 1ONV 2K7L
Enriched GO Terms of Interacting Partners?		Nuclear Receptor Activity Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Intracellular Receptor Signaling Pathway Nuclear Steroid Receptor Activity Intracellular Signal Transduction Positive Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of MiRNA Transcription Sequence-specific DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MiRNA Metabolic Process Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Negative Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Hormone-mediated Signaling Pathway Regulation Of RNA Metabolic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MiRNA Transcription Negative Regulation Of Biosynthetic Process Regulation Of Multicellular Organismal Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Developmental Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Macromolecule Metabolic Process Transcription Coregulator Binding Rhythmic Process Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Metabolic Process Chromatin Binding Negative Regulation Of Metabolic Process Estrogen Response Element Binding Response To Lipid Transcription By RNA Polymerase II Peroxisome Proliferator Activated Receptor Signaling Pathway	Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription, Elongation Core Mediator Complex Mediator Complex RNA Polymerase II Preinitiation Complex Assembly RNA Metabolic Process Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Nucleoplasm Nucleic Acid Metabolic Process Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Initiation Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Protein-DNA Complex Assembly Nucleobase-containing Compound Biosynthetic Process Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Initiation Surveillance Positive Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Elongation By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Transcription Coregulator Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-templated Transcription Elongation Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Nuclear Vitamin D Receptor Binding DNA-templated Transcription Nuclear RNA Surveillance Positive Regulation Of Biosynthetic Process INTAC Complex RNA Surveillance DNA-templated Transcription Initiation
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