NUP58 and MIS18A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NUP58	MIS18A
Description		nucleoporin 58	MIS18 kinetochore protein A
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Membrane Nuclear Membrane Protein-containing Complex	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol CENP-A Recruiting Complex
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein-containing Complex Binding	Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Nucleocytoplasmic Transport Protein Transport Regulation Of Protein Import Into Nucleus MRNA Transport	Chromosome Segregation Heterochromatin Formation CENP-A Containing Chromatin Assembly Cell Division Protein Localization To Chromosome, Centromeric Region Pericentric Heterochromatin Organization
Pathways			Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS
Interacting Genes		19 interacting genes: ABI3 AGR2 APC COG3 COG6 HTT KRT27 KRT28 KRT33B MAPK3 MEIS2 MIS18A NUP62 PKNOX1 PKNOX2 TRAF1 TRIM54 UBQLN1 UBQLN2	30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CNGA3 DMAP1 FNDC11 GCSH GLYCTK IFT20 MAFIP MBIP MIS18BP1 NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA VMA22 ZNF471 ZNF655
Entrez ID		9818	54069
HPRD ID		06355	10749
Ensembl ID		ENSG00000139496	ENSG00000159055
Uniprot IDs		A0A8Q3WKK5 A0A8Q3WKL7 Q9BVL2	Q9NYP9
PDB IDs		4JO7 4JO9 4JQ5 5IJN 5IJO 7PER 7R5J 7R5K	7SFY 7SFZ 8S30
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Localization To Centrosome Regulation Of Protein Localization To Centrosome Organelle Organization Regulation Of Macroautophagy Structural Constituent Of Skin Epidermis Intermediate Filament Organization Positive Regulation Of Response To Endoplasmic Reticulum Stress Golgi Transport Complex Retrograde Transport, Vesicle Recycling Within Golgi Anatomical Structure Morphogenesis Autophagosome Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Autophagosome Assembly Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of ERAD Pathway Regulation Of Organelle Assembly Autophagosome Organization Regulation Of Organelle Organization Golgi Organization Regulation Of ERAD Pathway Positive Regulation Of Catabolic Process Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Hair Follicle Morphogenesis Identical Protein Binding Positive Regulation Of ERBB Signaling Pathway Intra-Golgi Vesicle-mediated Transport Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule Depolymerization Regulation Of Protein Catabolic Process Regulation Of Protein Stability Regulation Of Autophagy Intermediate Filament Polyubiquitin Modification-dependent Protein Binding Negative Regulation Of Microtubule Polymerization Or Depolymerization Cytoskeleton Epithelial Cell Differentiation Structural Molecule Activity Vacuole Organization Negative Regulation Of Store-operated Calcium Channel Activity Tissue Morphogenesis Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Peptidyl-tyrosine Phosphorylation Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of G Protein-coupled Receptor Internalization	Pericentric Heterochromatin Organization CENP-A Recruiting Complex Autophagosome Membrane Docking Swr1 Complex CENP-A Containing Chromatin Assembly Organelle Localization By Membrane Tethering
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