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MIS18A

Description MIS18 kinetochore protein A
Image
GO Annotations Cellular Component
  • Chromosome, Centromeric Region
  • Chromatin
  • Nucleus
  • Nucleoplasm
  • Chromosome
  • Cytosol
  • CENP-A Recruiting Complex
Molecular Function
  • Protein Binding
  • Protein-macromolecule Adaptor Activity
  • Identical Protein Binding
  • Metal Ion Binding
Biological Process
  • Chromosome Segregation
  • Heterochromatin Formation
  • CENP-A Containing Chromatin Assembly
  • Cell Division
  • Protein Localization To Chromosome, Centromeric Region
  • Pericentric Heterochromatin Organization
Pathways
  • Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS
Interacting Genes 30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CNGA3 DMAP1 FNDC11 GCSH GLYCTK IFT20 MAFIP MBIP MIS18BP1 NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA VMA22 ZNF471 ZNF655
Entrez ID 54069
HPRD ID 10749
Ensembl ID ENSG00000159055
Uniprot IDs Q9NYP9
PDB IDs 7SFY 7SFZ 8S30
Enriched GO Terms of Interacting Partners?
  • Pericentric Heterochromatin Organization
  • CENP-A Recruiting Complex
  • Autophagosome Membrane Docking
  • Swr1 Complex
  • CENP-A Containing Chromatin Assembly
  • Organelle Localization By Membrane Tethering
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