NUPL1 and NUP62

Number of citations of the paper that reports this interaction (PMID 11266456)
77

Data Source:
BioGRID (two hybrid)
HPRD (in vitro)

		NUPL1	NUP62
Gene Name		nucleoporin like 1	nucleoporin 62kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Nuclear Pore Nuclear Membrane	Spindle Pole Nuclear Envelope Nuclear Pore Cytoplasm Ribonucleoprotein Complex Nucleocytoplasmic Shuttling Complex Nuclear Membrane Intracellular Membrane-bounded Organelle Pore Complex
	Molecular Function	Nucleocytoplasmic Transporter Activity Protein Binding	Chromatin Binding Nucleocytoplasmic Transporter Activity Protein Binding Structural Constituent Of Nuclear Pore Receptor Signaling Complex Scaffold Activity SH2 Domain Binding Ubiquitin Binding Thyroid Hormone Receptor Binding PTB Domain Binding
	Biological Process	Mitotic Cell Cycle Carbohydrate Metabolic Process Nucleocytoplasmic Transport Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process MRNA Transport Transmembrane Transport	Mitotic Cell Cycle Carbohydrate Metabolic Process Transcription, DNA-templated Nucleocytoplasmic Transport Mitotic Nuclear Envelope Disassembly Cell Surface Receptor Signaling Pathway Cell Aging Cell Death Negative Regulation Of Cell Proliferation Hexose Transport Pathogenesis Hormone-mediated Signaling Pathway Regulation Of Signal Transduction Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of MAP Kinase Activity Small Molecule Metabolic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Regulation Of Ras Protein Signal Transduction Negative Regulation Of Ras Protein Signal Transduction MRNA Transport Transmembrane Transport
Pathways			Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ABI3 APC HTT MAPK3 NUP54 NUP62 TRAF1 UBQLN1	65 interactors: ABI2 ADAM15 AGR3 ATXN7 BFSP1 BLOC1S6 C1orf216 CCDC121 CCDC146 CCDC150 CCDC153 CCDC53 CCHCR1 CENPU CEP57L1 CLIC1 CRCT1 DDX3X DGCR6 DTNB FABP3 GOPC GORASP2 GTF2E2 HAUS1 HSF2 IFT20 IK IKBIP IPO5 ISCU KANSL1 KIFC3 KLHL32 KPNA1 KPNA2 KPNB1 KRT20 LMO2 MUC1 MYO15B NFX1 NUP153 NUP54 NUP98 NUPL1 NUTF2 NXF1 NXF2 OGT OIP5 PBX2 PHF21A PIN1 PTMA RANBP2 SMARCE1 SNAPC5 SP1 SSC5D THAP1 TRAF3 TXLNA XPO1 XPO6
Entrez ID		9818	23636
HPRD ID		06355	05782
Ensembl ID		ENSG00000139496	ENSG00000213024
Uniprot IDs		Q9BVL2	P37198
PDB IDs			2H4D
Enriched GO Terms of Interacting Partners?		Cell Death Death Cell Cycle Mitotic Cell Cycle Process Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Signal Transduction Mitotic Nuclear Envelope Disassembly Mitotic Cell Cycle Nucleocytoplasmic Transport Nuclear Transport Nuclear Envelope Disassembly Regulation Of Intracellular Signal Transduction Regulation Of Signaling Apoptotic Process Programmed Cell Death Nuclear Envelope Organization Cell Aging Cell Cycle Process Glucose Transport Hexose Transport Endomembrane System Organization Neural Plate Formation Negative Regulation Of Apolipoprotein Binding Cytokine-mediated Signaling Pathway Viral Transcription Positive Regulation Of Signal Transduction Regulation Of Glucose Transport Viral Process Serotonin Uptake Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Lactate Biosynthetic Process From Pyruvate MRNA Transport Nucleus Organization Cellular Response To Cytokine Stimulus Carbohydrate Transport Cellular Response To Stimulus Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Phosphorus Metabolic Process Regulation Of MAPK Cascade Movement Of Cell Or Subcellular Component RNA Transport Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Protein Phosphatase Type 2A Activity RNA Localization Negative Regulation Of MAPK Cascade Negative Regulation Of Cell Proliferation Cytoplasmic Transport Quinolinate Biosynthetic Process	Nucleocytoplasmic Transport Nuclear Transport Viral Process Cytoplasmic Transport MRNA Transport RNA Transport RNA Localization Intracellular Transport Nuclear Import Nucleus Organization Viral Life Cycle NLS-bearing Protein Import Into Nucleus Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Establishment Of Localization In Cell Protein Transport Protein Localization To Nucleus Cytokine-mediated Signaling Pathway Establishment Of Protein Localization Nuclear Export Cellular Localization Protein Import Into Nucleus Protein Export From Nucleus Intracellular Transport Of Virus Nuclear Envelope Organization Glucose Transport Protein Localization Cellular Response To Cytokine Stimulus Organelle Organization Protein Import Mitotic Cell Cycle Hexose Transport Cellular Protein Localization Viral Transcription Regulation Of Glucose Transport Response To Cytokine RNA Biosynthetic Process Intracellular Protein Transport Cell Cycle Carbohydrate Transport Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Cellular Response To Organic Substance Protein Localization To Organelle Gene Expression Response To Organic Substance Protein Targeting Nuclear Pore Complex Assembly Pathogenesis Establishment Of Protein Localization To Organelle Ribosomal Protein Import Into Nucleus
Tagcloud ?		amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape lnx2 mapping notch offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt	barr bblf2 bblf4 betaherpesviruses bglf4 bslf1 cotransfected dilation ebv egress epstein fg gammaherpesviruses gateways import importin lytic mpm nls nlss nucleocapsids nucleocytoplasmic nucleoporins nup153 nups pore reorganization replicating vca
Tagcloud (Difference) ?		amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape lnx2 mapping notch offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt	barr bblf2 bblf4 betaherpesviruses bglf4 bslf1 cotransfected dilation ebv egress epstein fg gammaherpesviruses gateways import importin lytic mpm nls nlss nucleocapsids nucleocytoplasmic nucleoporins nup153 nups pore reorganization replicating vca
Tagcloud (Intersection) ?