MIS18A and TEDC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MIS18A	TEDC2
Description		MIS18 kinetochore protein A	tubulin epsilon and delta complex 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol CENP-A Recruiting Complex	Cytoplasm Centriole Cytoskeleton Cilium Cell Projection
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Chromosome Segregation Heterochromatin Formation CENP-A Containing Chromatin Assembly Cell Division Protein Localization To Chromosome, Centromeric Region Pericentric Heterochromatin Organization	Positive Regulation Of Smoothened Signaling Pathway
Pathways		Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS
Interacting Genes		30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CNGA3 DMAP1 FNDC11 GCSH GLYCTK IFT20 MAFIP MBIP MIS18BP1 NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA VMA22 ZNF471 ZNF655	11 interacting genes: FEZ1 FEZ2 KDM1A KRT27 KRTAP10-3 KRTAP10-7 KRTAP10-9 MDFI MIS18A NOTCH2NLA OGT
Entrez ID		54069	80178
HPRD ID		10749	07840
Ensembl ID		ENSG00000159055	ENSG00000162062
Uniprot IDs		Q9NYP9	Q7L2K0
PDB IDs		7SFY 7SFZ 8S30
Enriched GO Terms of Interacting Partners?		Pericentric Heterochromatin Organization CENP-A Recruiting Complex Autophagosome Membrane Docking Swr1 Complex CENP-A Containing Chromatin Assembly Organelle Localization By Membrane Tethering	Keratin Filament Intermediate Filament Negative Regulation Of Autophagosome Assembly Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Macroautophagy Regulation Of Autophagosome Assembly Regulation Of Vacuole Organization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Negative Regulation Of Cellular Component Organization Cerebral Cortex Development Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Catabolic Process Protein O-acetylglucosaminyltransferase Activity Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Pericentric Heterochromatin Organization CENP-A Recruiting Complex Negative Regulation Of Autophagy
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