MIS18A and MIS18BP1

Number of citations of the paper that reports this interaction (PubMedID 28059702)
64

Data Source:
BioGRID (biochemical, pull down)

		MIS18A	MIS18BP1
Description		MIS18 kinetochore protein A	MIS18 binding protein 1
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol CENP-A Recruiting Complex	Chromosome, Centromeric Region Nucleus Nucleoplasm Chromosome CENP-A Recruiting Complex
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Metal Ion Binding	DNA Binding Protein Binding
	Biological Process	Chromosome Segregation Heterochromatin Formation CENP-A Containing Chromatin Assembly Cell Division Protein Localization To Chromosome, Centromeric Region Pericentric Heterochromatin Organization	CENP-A Containing Chromatin Assembly Cell Division Pericentric Heterochromatin Organization
Pathways		Deposition of new CENPA-containing nucleosomes at the centromere	Deposition of new CENPA-containing nucleosomes at the centromere Cyclin A/B1/B2 associated events during G2/M transition
Drugs
Diseases
GWAS			Shoulder impingement ( 33482370) Sjögren's syndrome ( 28076899)
Interacting Genes		30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CNGA3 DMAP1 FNDC11 GCSH GLYCTK IFT20 MAFIP MBIP MIS18BP1 NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA VMA22 ZNF471 ZNF655	6 interacting genes: CDK1 FBXO7 MIS18A OIP5 PCBD1 SP1
Entrez ID		54069	55320
HPRD ID		10749	12629
Ensembl ID		ENSG00000159055	ENSG00000129534
Uniprot IDs		Q9NYP9	Q6P0N0
PDB IDs		7SFY 7SFZ 8S30	1WGX 8S31
Enriched GO Terms of Interacting Partners?		Pericentric Heterochromatin Organization CENP-A Recruiting Complex Autophagosome Membrane Docking Swr1 Complex CENP-A Containing Chromatin Assembly Organelle Localization By Membrane Tethering	Pericentric Heterochromatin Organization CENP-A Recruiting Complex CENP-A Containing Chromatin Assembly Protein Localization To Chromosome, Centromeric Region Nucleoplasm Protein Localization To Chromosome Pronuclear Fusion Mitotic DNA-templated DNA Replication Cyclin B1-CDK1 Complex Cyclin A1-CDK1 Complex Cyclin A2-CDK1 Complex Cell Division 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Tyrosine Biosynthetic Process Phenylalanine 4-monooxygenase Activity Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Positive Regulation Of Hydrogen Sulfide Biosynthetic Process Cellular Response To Wortmannin Response To Wortmannin Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Chromatin Remodeling Mitotic DNA Replication DNA Synthesis Involved In Mitotic DNA Replication Cyclin-dependent Protein Kinase Activity Heterochromatin Formation Chromosome Segregation Lewy Body Core Regulation Of Schwann Cell Differentiation Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Identical Protein Binding Chromosome, Centromeric Region Negative Regulation Of Gene Expression, Epigenetic Regulation Of Metabolic Process Thymidine Biosynthetic Process Chromatin Organization Golgi Disassembly Nuclear DNA Replication Histone Kinase Activity Cellular Response To Zinc Ion Starvation Negative Regulation Of Mitotic Cell Cycle Thymidine Metabolic Process Tetrahydrobiopterin Biosynthetic Process Negative Regulation Of Cell Cycle Phase Transition Nucleus Positive Regulation Of Mitotic Sister Chromatid Segregation Tetrahydrobiopterin Metabolic Process
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