MIS18A and VMA22

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MIS18A	VMA22
Description		MIS18 kinetochore protein A	vacuolar ATPase assembly factor VMA22
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol CENP-A Recruiting Complex	Lysosome Endosome Vacuole Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Vacuolar Proton-transporting V-type ATPase Complex COPI-coated Vesicle Cytoplasmic Vesicle
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Metal Ion Binding	Protein Binding Unfolded Protein Binding
	Biological Process	Chromosome Segregation Heterochromatin Formation CENP-A Containing Chromatin Assembly Cell Division Protein Localization To Chromosome, Centromeric Region Pericentric Heterochromatin Organization	Intracellular Iron Ion Homeostasis Lysosomal Lumen Acidification Cellular Response To Increased Oxygen Levels Vacuolar Proton-transporting V-type ATPase Complex Assembly Lysosomal Protein Catabolic Process
Pathways		Deposition of new CENPA-containing nucleosomes at the centromere	RHOA GTPase cycle
Drugs
Diseases
GWAS
Interacting Genes		30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CNGA3 DMAP1 FNDC11 GCSH GLYCTK IFT20 MAFIP MBIP MIS18BP1 NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA VMA22 ZNF471 ZNF655	9 interacting genes: ABI2 ALOX15B APP CSNK2B MIS18A NTAQ1 PLK1 PRKCZ TK1
Entrez ID		54069	84317
HPRD ID		10749	14428
Ensembl ID		ENSG00000159055	ENSG00000136710
Uniprot IDs		Q9NYP9	B8ZZ99 Q96NT0
PDB IDs		7SFY 7SFZ 8S30
Enriched GO Terms of Interacting Partners?		Pericentric Heterochromatin Organization CENP-A Recruiting Complex Autophagosome Membrane Docking Swr1 Complex CENP-A Containing Chromatin Assembly Organelle Localization By Membrane Tethering	Phosphate-containing Compound Metabolic Process Cytosol Phosphorylation Protein Phosphorylation Identical Protein Binding Nucleus Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Chemokine Production Endocannabinoid Signaling Pathway Linoleate 9S-lipoxygenase Activity Linoleate 13S-lipoxygenase Activity Anchoring Junction Cannabinoid Biosynthetic Process Arachidonate 15-lipoxygenase Activity Arachidonate 8(S)-lipoxygenase Activity Lipoxin A4 Biosynthetic Process Lipoxin Biosynthetic Process Lipoxin A4 Metabolic Process Cannabinoid Signaling Pathway Positive Regulation Of Chemokine Production Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Protein Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Proteolysis Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Protein Catabolic Process Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Modulation Of Excitatory Postsynaptic Potential Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Protein Modification Process Protein Kinase CK2 Complex Protein Serine/threonine Kinase Activity Symbiont-mediated Disruption Of Host Cell PML Body Protein Localization To Chromosome Synaptonemal Complex Disassembly Golgi Inheritance DNA Synthesis Involved In Mitotic DNA Replication
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