MIS18A and CNGA3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MIS18A	CNGA3
Description		MIS18 kinetochore protein A	cyclic nucleotide gated channel subunit alpha 3
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol CENP-A Recruiting Complex	Plasma Membrane Membrane Intracellular Cyclic Nucleotide Activated Cation Channel Complex Dendrite Neuronal Cell Body Axon Initial Segment Perikaryon Glial Cell Projection Transmembrane Transporter Complex
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Metal Ion Binding	Nucleotide Binding Monoatomic Ion Channel Activity Intracellularly Cyclic Nucleotide-activated Monoatomic Cation Channel Activity Intracellularly CAMP-activated Cation Channel Activity Intracellularly CGMP-activated Cation Channel Activity Calcium Channel Activity Sodium Channel Activity Protein Binding Ligand-gated Monoatomic Ion Channel Activity Myosin Binding CGMP Binding Cadherin Binding
	Biological Process	Chromosome Segregation Heterochromatin Formation CENP-A Containing Chromatin Assembly Cell Division Protein Localization To Chromosome, Centromeric Region Pericentric Heterochromatin Organization	Monoatomic Ion Transport Monoatomic Cation Transport Sodium Ion Transport Calcium Ion Transport Signal Transduction Visual Perception Response To Magnesium Ion Monoatomic Ion Transmembrane Transport Sodium Ion Transmembrane Transport Response To CAMP Transmembrane Transport Retina Development In Camera-type Eye Calcium Ion Transmembrane Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Import Across Plasma Membrane
Pathways		Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases			Achromatopsia; Rod monochromacy
GWAS
Interacting Genes		30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CNGA3 DMAP1 FNDC11 GCSH GLYCTK IFT20 MAFIP MBIP MIS18BP1 NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA VMA22 ZNF471 ZNF655	2 interacting genes: MIS18A TRIM54
Entrez ID		54069	1261
HPRD ID		10749	02504
Ensembl ID		ENSG00000159055	ENSG00000144191
Uniprot IDs		Q9NYP9	Q16281
PDB IDs		7SFY 7SFZ 8S30	3SWY 7RHS 8ETP 8EU3 8EUC 8EV8 8EV9 8EVA 8EVB 8EVC
Enriched GO Terms of Interacting Partners?		Pericentric Heterochromatin Organization CENP-A Recruiting Complex Autophagosome Membrane Docking Swr1 Complex CENP-A Containing Chromatin Assembly Organelle Localization By Membrane Tethering	Pericentric Heterochromatin Organization CENP-A Recruiting Complex CENP-A Containing Chromatin Assembly
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