FAM65B and PER1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		FAM65B	PER1
Gene Name		family with sequence similarity 65, member B	period circadian clock 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Cytoskeleton Filopodium Stereocilium Membrane	Nucleus Cytoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Binding Transcription Factor Activity Signal Transducer Activity Transcription Factor Binding Kinase Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding E-box Binding
	Biological Process	Muscle Organ Development Sensory Perception Of Sound Cell Differentiation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sodium Ion Transport Transcription, DNA-templated Signal Transduction Circadian Rhythm Entrainment Of Circadian Clock Posttranscriptional Regulation Of Gene Expression Circadian Regulation Of Gene Expression Regulation Of Hair Cycle Regulation Of Circadian Rhythm Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Entrainment Of Circadian Clock By Photoperiod Histone H3 Acetylation Histone H4 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of JNK Cascade Response To CAMP Histone H3 Deacetylation Circadian Regulation Of Translation Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of P38MAPK Cascade Negative Regulation Of Glucocorticoid Receptor Signaling Pathway
Pathways			BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS		Electroencephalographic traits in alcoholism ( 22554406)
Protein-Protein Interactions		5 interactors: MAP2K2 PER1 RHOA RHOC YWHAG	13 interactors: CCDC57 CRY1 CRY2 CSNK1D CSNK1E CSNK1G2 FAM65B GPRASP1 HIF1A PER2 PER3 RBPMS TIMELESS
Entrez ID		9750	5187
HPRD ID		12881	03774
Ensembl ID		ENSG00000111913	ENSG00000179094
Uniprot IDs		F5GX51 F5H029 Q9Y4F9	O15534
PDB IDs			1UL6
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Satellite Cell Migration Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Signal Transduction Wound Healing, Spreading Of Cells Positive Regulation Of Signal Transduction Regulation Of Signaling Axon Guidance Regulation Of Intracellular Transport Morphogenesis Of An Epithelial Sheet Apical Junction Assembly Generation Of Neurons Axonogenesis Neurogenesis Axon Development Regulation Of Intracellular Signal Transduction Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Small GTPase Mediated Signal Transduction Response To External Stimulus Vascular Endothelial Growth Factor Receptor Signaling Pathway Intracellular Signal Transduction Neuron Projection Morphogenesis Cytokinesis Cell-cell Junction Assembly Cell Morphogenesis Involved In Differentiation Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Response To Organonitrogen Compound Nervous System Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Organelle Organization Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Organic Substance Regulation Of Stress-activated MAPK Cascade Neuron Development Cell Junction Assembly Cell-cell Junction Organization Regulation Of Cellular Localization Signaling Cell Cycle Process Regulation Of Golgi Inheritance Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cell Morphogenesis Ras Protein Signal Transduction Cell Communication Neurotrophin Signaling Pathway Circadian Regulation Of Translation	Regulation Of Circadian Rhythm Circadian Rhythm Circadian Regulation Of Gene Expression Rhythmic Process Negative Regulation Of Circadian Rhythm Blue Light Signaling Pathway Response To Blue Light Regulation Of Signaling Lactate Metabolic Process Regulation Of Signal Transduction Negative Regulation Of Glucocorticoid Receptor Signaling Pathway Nitrogen Compound Metabolic Process Protein-chromophore Linkage Negative Regulation Of Transcription From RNA Polymerase II Promoter Peptidyl-serine Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Entrainment Of Circadian Clock By Photoperiod Positive Regulation Of Wnt Signaling Pathway Regulation Of Cell Shape Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Photoperiodism Entrainment Of Circadian Clock Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Glucose Homeostasis Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Signal Transduction Regulation Of Hormone Secretion Cell Cycle Phase Transition Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Wnt Signaling Pathway RNA Metabolic Process Gluconeogenesis Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Wnt Signaling Pathway Hexose Biosynthetic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of DNA-templated Transcription, Termination
Tagcloud ?		ambient atmosphere attached cd41 cd44 co2 colonies doubly epitopes exceeded formerly hypoxic immuno labeled lef1 li mf12 mimic monolayers n2 niches normoxia normoxic pc3 reconstitute res sorted waxman zhang	acutely afternoon bmal1 boivin bright cermakian circadian clock clocks cortef cuesta desynchronization entrain entrained glucocorticoids innovative jet lag night pbmcs per2 reset rhythms shifted synchronize synchronizers synchronizing travelers underlines
Tagcloud (Difference) ?		ambient atmosphere attached cd41 cd44 co2 colonies doubly epitopes exceeded formerly hypoxic immuno labeled lef1 li mf12 mimic monolayers n2 niches normoxia normoxic pc3 reconstitute res sorted waxman zhang	acutely afternoon bmal1 boivin bright cermakian circadian clock clocks cortef cuesta desynchronization entrain entrained glucocorticoids innovative jet lag night pbmcs per2 reset rhythms shifted synchronize synchronizers synchronizing travelers underlines
Tagcloud (Intersection) ?