RIPOR2

Description		RHO family interacting cell polarization regulator 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Apical Plasma Membrane Filopodium Stereocilium Cell Projection Stereocilium Membrane Actin-based Cell Projection
	Molecular Function	Protein Binding 14-3-3 Protein Binding
	Biological Process	Chemotaxis Cell Adhesion Negative Regulation Of Cell Adhesion Muscle Organ Development Sensory Perception Of Sound Negative Regulation Of Signal Transduction Cell Differentiation Negative Regulation Of Rho Protein Signal Transduction Negative Regulation Of T Cell Proliferation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Filopodium Assembly Regulation Of Cell Cycle Positive Regulation Of Neutrophil Chemotaxis Regulation Of Mitotic Spindle Assembly Positive Regulation Of Myoblast Fusion Negative Regulation Of Establishment Of T Cell Polarity Negative Regulation Of Protein Localization To Cell Leading Edge Cellular Response To Chemokine Regulation Of Establishment Of Cell Polarity Positive Regulation Of Neutrophil Extravasation Negative Regulation Of T Cell Migration Negative Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514)
Interacting Genes		6 interacting genes: MAP2K2 MTNR1B PER1 RHOA RHOC YWHAG
Entrez ID		9750
HPRD ID		12881
Ensembl ID		ENSG00000111913
Uniprot IDs		A0A2R8Y7B3 A0A2R8YEE0 B7Z5J9 B7Z6D6 B7Z6U4 F5GX51 F5H029 Q9Y4F9
PDB IDs
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Satellite Cell Migration Positive Regulation Of Lipase Activity Apical Junction Assembly Regulation Of Intracellular Signal Transduction Regulation Of Catalytic Activity Regulation Of Signal Transduction Negative Regulation Of Intracellular Signal Transduction Wound Healing, Spreading Of Cells Regulation Of Protein Kinase Activity Regulation Of Cell Communication Regulation Of Kinase Activity Regulation Of Signaling Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Catalytic Activity Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Stress Fiber Assembly Cleavage Furrow Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Vasoconstriction Positive Regulation Of Actin Filament Bundle Assembly Mitotic Cytokinesis Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Focal Adhesion Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Mitotic Cleavage Furrow Formation Cytoskeleton-dependent Cytokinesis Regulation Of Stress Fiber Assembly Regulation Of Phosphorus Metabolic Process Aortic Valve Formation Cell-cell Junction Assembly Positive Regulation Of Hydrolase Activity Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Cytoplasmic Side Of Plasma Membrane Positive Regulation Of Cell Motility Positive Regulation Of Vascular Associated Smooth Muscle Contraction Endothelial Tube Lumen Extension Positive Regulation Of Locomotion Regulation Of Multicellular Organismal Process Negative Regulation Of Cell Communication Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Circadian Rhythm Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Protein Modification Process Beta Selection Protein Kinase C Inhibitor Activity Blood Vessel Diameter Maintenance
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