ACAP1 and VAMP3

Number of citations of the paper that reports this interaction (PMID 15525538)
20

Data Source:
HPRD (in vivo, in vitro)

		ACAP1	VAMP3
Gene Name		ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	vesicle-associated membrane protein 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane Recycling Endosome Membrane	Intracellular Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Integral Component Of Membrane Apical Plasma Membrane Cell Junction Clathrin-coated Vesicle Secretory Granule Clathrin-coated Vesicle Membrane SNARE Complex Neuron Projection Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	ARF GTPase Activator Activity Zinc Ion Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin-1 Binding
	Biological Process	Protein Transport Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity	Positive Regulation Of Receptor Recycling Protein Complex Assembly Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Neurotransmitter Secretion Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Substrate Adhesion-dependent Cell Spreading SNARE Complex Assembly Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Positive Regulation Of Immunoglobulin Secretion Membrane Fusion Mucus Secretion Negative Regulation Of Secretion By Cell Regulation Of Histamine Secretion By Mast Cell
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 21102463) Periodontal microbiota ( 22699663)
Protein-Protein Interactions		5 interactors: AKT1 IFFO1 ITGB1 TFRC VAMP3	14 interactors: ACAP1 APP BCAP31 BCL2L13 DDB1 IKBKG NELFE SNAP23 STX16 STX2 STX3 STX4 VAMP2 VAMP8
Entrez ID		9744	9341
HPRD ID		08474	04711
Ensembl ID		ENSG00000072818	ENSG00000049245
Uniprot IDs		Q15027	Q15836 Q6FGG2 Q9BRV4
PDB IDs		3JUE 3T9K 4F1P
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Protein Transport Establishment Of Protein Localization Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Protein Localization To Plasma Membrane Cellular Response To Mechanical Stimulus Protein Localization Maternal Process Involved In Female Pregnancy Glycogen Cell Differentiation Involved In Embryonic Placenta Development Membrane Organization Chemical Homeostasis Intracellular Protein Transport G1/S Transition Of Mitotic Cell Cycle Regulation Of Cellular Localization Cell-substrate Adhesion Cell Differentiation Response To Mechanical Stimulus Regulation Of Collagen Catabolic Process Plasma Membrane Organization Striated Muscle Cell Differentiation Female Pregnancy Calcium-independent Cell-matrix Adhesion Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Negative Regulation Of Fatty Acid Beta-oxidation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Protein Localization Homeostatic Process Formation Of Radial Glial Scaffolds Response To UV-A Intracellular Transport Muscle Cell Differentiation Activation-induced Cell Death Of T Cells Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Leukocyte Differentiation Response To Light Stimulus Positive Regulation Of Cellular Component Movement Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Positive Regulation Of Locomotion Positive Regulation Of Cell Adhesion Regulation Of Neuron Projection Development SNARE Complex Assembly Regulation Of Cellular Amino Acid Metabolic Process Cellular Response To Organic Cyclic Compound Negative Regulation Of Transport Negative Regulation Of Fatty Acid Oxidation	Vesicle Fusion Organelle Fusion Membrane Fusion Vesicle Organization Synaptic Vesicle Fusion To Presynaptic Membrane Synaptic Vesicle Exocytosis Exocytosis Establishment Of Vesicle Localization Vesicle Localization Neurotransmitter Secretion Synaptic Vesicle Transport Golgi Vesicle Transport Secretion By Cell Establishment Of Localization In Cell Regulation Of Neurotransmitter Levels Protein Transport Vesicle-mediated Transport Establishment Of Organelle Localization Establishment Of Protein Localization Intracellular Transport Secretion Neurotransmitter Transport Cellular Localization Organelle Localization Vesicle Docking Post-Golgi Vesicle-mediated Transport Protein Localization Membrane Organization Membrane Docking Long-term Synaptic Potentiation Regulation Of Protein Localization To Plasma Membrane Intracellular Protein Transport Positive Regulation Of Protein Localization To Cell Surface SNARE Complex Assembly Synaptic Transmission Positive Regulation Of Synaptic Transmission Regulation Of Protein Localization To Cell Surface Positive Regulation Of Regulated Secretory Pathway Cellular Protein Localization Transport Positive Regulation Of Peptidase Activity Response To Hydroperoxide Regulation Of Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Signaling Regulation Of Synaptic Plasticity Cell-cell Signaling Organelle Organization Positive Regulation Of Catalytic Activity Endoplasmic Reticulum Calcium Ion Homeostasis
Tagcloud ?			cellubrevin coimmunoprecipitation consistent cytoplasmic deleted domains glut1 glut4 immunoprecipitation insulin introduction membrane microinjection neither plasma recombinant requirement responsive resulted site snap stimulated syntaxin translocation vaccinia vamp2 vesicle vesicles
Tagcloud (Difference) ?			cellubrevin coimmunoprecipitation consistent cytoplasmic deleted domains glut1 glut4 immunoprecipitation insulin introduction membrane microinjection neither plasma recombinant requirement responsive resulted site snap stimulated syntaxin translocation vaccinia vamp2 vesicle vesicles
Tagcloud (Intersection) ?