ACAP1 and IFFO1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ACAP1	IFFO1
Description		ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	intermediate filament family orphan 1
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GO Annotations	Cellular Component	Cytoplasm Endosome Membrane Recycling Endosome Membrane	Nucleus Nuclear Inner Membrane Nucleoplasm Intermediate Filament Membrane Nuclear Matrix Site Of Double-strand Break
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Protein Transport	Double-strand Break Repair Via Nonhomologous End Joining Protein Localization To Site Of Double-strand Break DNA Double-strand Break Attachment To Nuclear Envelope
Pathways
Drugs
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Systemic lupus erythematosus ( 33272962 33536424) White blood cell count ( 32888494)	Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		12 interacting genes: AKT1 FCHSD2 GRB2 IFFO1 ITGB1 NEBL RABGAP1L SH3RF1 SNCA TFRC UQCRB VAMP3	8 interacting genes: ACAP1 GFI1B LMNA NDN RHOU RNF183 TCHP XRCC4
Entrez ID		9744	25900
HPRD ID		08474	09988
Ensembl ID		ENSG00000072818	ENSG00000010295
Uniprot IDs		Q15027	A0A087WZ16 B4DQQ1 Q0D2I5 Q6P593
PDB IDs		3JUE 3T9K 4CKG 4CKH 4F1P 4NSW 5H3D	6ABO
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Receptor Internalization Receptor-mediated Endocytosis Endocytosis Import Into Cell Recycling Endosome Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Protein Localization To Cell Periphery SNARE Complex Assembly Positive Regulation Of Receptor Recycling Regulation Of Cell Activation Positive Regulation Of Fibroblast Migration Perinuclear Region Of Cytoplasm Regulation Of Neurotransmitter Uptake Endosome Regulation Of T Cell Activation Regulation Of Receptor Recycling Phosphatidylinositol-3,4-bisphosphate Binding Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Regulation Of Protein Localization To Cell Periphery Cell Cortex Protein Kinase Binding Cellular Response To Low-density Lipoprotein Particle Stimulus Cell Migration Involved In Sprouting Angiogenesis Regulation Of Protein Localization Positive Regulation Of Protein Localization Negative Regulation Of Programmed Cell Death Regulation Of Protein-containing Complex Assembly Organelle Localization Response To Iron Ion Response To Copper Ion Lamellipodium Golgi To Plasma Membrane Protein Transport Blood Vessel Endothelial Cell Migration Cellular Response To Lipoprotein Particle Stimulus Phosphatidylinositol-3,4,5-trisphosphate Binding Positive Regulation Of Organelle Organization Regulation Of Lymphocyte Activation Regulation Of Immune System Process Regulation Of Fibroblast Migration Response To Cytokine T Cell Costimulation Response To Peptide Postsynapse Positive Regulation Of Actin Filament Polymerization Hsp70 Protein Binding Protein Transport Positive Regulation Of Cellular Component Organization
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