VAMP3 and STX2

Number of citations of the paper that reports this interaction (PMID 12828989)
5

Data Source:
BioGRID (two hybrid)

		VAMP3	STX2
Gene Name		vesicle-associated membrane protein 3	syntaxin 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Integral Component Of Membrane Apical Plasma Membrane Cell Junction Clathrin-coated Vesicle Secretory Granule Clathrin-coated Vesicle Membrane SNARE Complex Neuron Projection Intracellular Membrane-bounded Organelle Recycling Endosome	Extracellular Space Plasma Membrane Cell-cell Junction Synaptic Vesicle Cell Surface Endomembrane System Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin-1 Binding	SNARE Binding SNAP Receptor Activity Protein Binding Protein Dimerization Activity Calcium-dependent Protein Binding
	Biological Process	Positive Regulation Of Receptor Recycling Protein Complex Assembly Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Neurotransmitter Secretion Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Substrate Adhesion-dependent Cell Spreading SNARE Complex Assembly Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Positive Regulation Of Immunoglobulin Secretion Membrane Fusion Mucus Secretion Negative Regulation Of Secretion By Cell Regulation Of Histamine Secretion By Mast Cell	Intracellular Protein Transport Signal Transduction Acrosome Reaction Ectoderm Development Organ Morphogenesis Cell Differentiation Regulation Of Blood Coagulation Synaptic Vesicle Fusion To Presynaptic Membrane Response To Hydroperoxide Vesicle Docking Protein Oligomerization Regulation Of Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Periodontal microbiota ( 22699663)
Protein-Protein Interactions		14 interactors: ACAP1 APP BCAP31 BCL2L13 DDB1 IKBKG NELFE SNAP23 STX16 STX2 STX3 STX4 VAMP2 VAMP8	12 interactors: CPLX2 SNAP23 SNAP25 STXBP1 STXBP2 SYT1 SYT4 SYT7 UNC13B VAMP2 VAMP3 VAPB
Entrez ID		9341	2054
HPRD ID		04711	11816
Ensembl ID		ENSG00000049245	ENSG00000111450
Uniprot IDs		Q15836 Q6FGG2 Q9BRV4	P32856
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Organelle Fusion Membrane Fusion Vesicle Organization Synaptic Vesicle Fusion To Presynaptic Membrane Synaptic Vesicle Exocytosis Exocytosis Establishment Of Vesicle Localization Vesicle Localization Neurotransmitter Secretion Synaptic Vesicle Transport Golgi Vesicle Transport Secretion By Cell Establishment Of Localization In Cell Regulation Of Neurotransmitter Levels Protein Transport Vesicle-mediated Transport Establishment Of Organelle Localization Establishment Of Protein Localization Intracellular Transport Secretion Neurotransmitter Transport Cellular Localization Organelle Localization Vesicle Docking Post-Golgi Vesicle-mediated Transport Protein Localization Membrane Organization Membrane Docking Long-term Synaptic Potentiation Regulation Of Protein Localization To Plasma Membrane Intracellular Protein Transport Positive Regulation Of Protein Localization To Cell Surface SNARE Complex Assembly Synaptic Transmission Positive Regulation Of Synaptic Transmission Regulation Of Protein Localization To Cell Surface Positive Regulation Of Regulated Secretory Pathway Cellular Protein Localization Transport Positive Regulation Of Peptidase Activity Response To Hydroperoxide Regulation Of Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Signaling Regulation Of Synaptic Plasticity Cell-cell Signaling Organelle Organization Positive Regulation Of Catalytic Activity Endoplasmic Reticulum Calcium Ion Homeostasis	Exocytosis Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Secretion By Cell Neurotransmitter Transport Secretion Regulation Of Exocytosis Vesicle Docking Vesicle-mediated Transport Membrane Docking Regulation Of Secretion Synaptic Vesicle Transport Synaptic Vesicle Exocytosis Vesicle Docking Involved In Exocytosis Establishment Of Localization In Cell Glutamate Secretion Cellular Localization Regulation Of Cellular Localization Regulation Of Vesicle-mediated Transport Establishment Of Vesicle Localization Vesicle Localization Cell-cell Signaling Establishment Of Organelle Localization Acid Secretion Organelle Localization Dicarboxylic Acid Transport Vesicle Organization Regulation Of Synaptic Transmission Synaptic Transmission Leukocyte Degranulation Transport Synaptic Vesicle Priming Vesicle Fusion Amino Acid Transport Regulation Of Calcium Ion-dependent Exocytosis Regulated Secretory Pathway Regulation Of Synaptic Plasticity Positive Regulation Of Exocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis Organelle Fusion Membrane Organization Positive Regulation Of Synaptic Transmission Carboxylic Acid Transport Organic Acid Transport Anion Transport Membrane Fusion Regulation Of Vesicle Fusion Leukocyte Activation Involved In Immune Response Endomembrane System Organization Organic Anion Transport
Tagcloud ?		cellubrevin coimmunoprecipitation consistent cytoplasmic deleted domains glut1 glut4 immunoprecipitation insulin introduction membrane microinjection neither plasma recombinant requirement responsive resulted site snap stimulated syntaxin translocation vaccinia vamp2 vesicle vesicles	alter apc apoptotic bcl2 challenged chop contributing cytoprotective decreasing dr5 enterohemorrhagic fold hemolytic hsp40 kidneys later producing ribotoxic rodentium saline shiga spliced toxigenic toxins transcripts untreated uremic xbp1
Tagcloud (Difference) ?		cellubrevin coimmunoprecipitation consistent cytoplasmic deleted domains glut1 glut4 immunoprecipitation insulin introduction membrane microinjection neither plasma recombinant requirement responsive resulted site snap stimulated syntaxin translocation vaccinia vamp2 vesicle vesicles	alter apc apoptotic bcl2 challenged chop contributing cytoprotective decreasing dr5 enterohemorrhagic fold hemolytic hsp40 kidneys later producing ribotoxic rodentium saline shiga spliced toxigenic toxins transcripts untreated uremic xbp1
Tagcloud (Intersection) ?