ACAP1

Name	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Structure
Interactors	12 interactors: AKT1 FCHSD2 GRB2 IFFO1 ITGB1 NEBL RABGAP1L SH3RF1 SNCA TFRC UQCRB VAMP3
GO Annotations	Cellular Component	Cytoplasm Endosome Membrane Recycling Endosome Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Protein Transport
GWAS	Autoimmune thyroid disease ( 32581359 ) Monocyte percentage of white cells ( 32888494 ) Neutrophil count ( 32888494 ) Systemic lupus erythematosus ( 33272962 33536424 ) White blood cell count ( 32888494 )
Entrez ID	9744
HPRD ID	08474
Ensembl ID	ENSG00000072818
Uniprot IDs	Q15027
PDB IDs	3JUE 3T9K 4CKG 4CKH 4F1P 4NSW 5H3D
GO Terms Enriched among Interactors ?	Vesicle-mediated Transport Receptor Internalization Receptor-mediated Endocytosis Endocytosis Import Into Cell Recycling Endosome Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Protein Localization To Cell Periphery SNARE Complex Assembly Positive Regulation Of Receptor Recycling Regulation Of Cell Activation Positive Regulation Of Fibroblast Migration Perinuclear Region Of Cytoplasm Regulation Of Neurotransmitter Uptake Endosome Regulation Of T Cell Activation Regulation Of Receptor Recycling Phosphatidylinositol-3,4-bisphosphate Binding Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Regulation Of Protein Localization To Cell Periphery Cell Cortex Protein Kinase Binding Cellular Response To Low-density Lipoprotein Particle Stimulus Cell Migration Involved In Sprouting Angiogenesis Regulation Of Protein Localization Positive Regulation Of Protein Localization Negative Regulation Of Programmed Cell Death Regulation Of Protein-containing Complex Assembly Organelle Localization Response To Iron Ion Response To Copper Ion Lamellipodium Golgi To Plasma Membrane Protein Transport Blood Vessel Endothelial Cell Migration Cellular Response To Lipoprotein Particle Stimulus Phosphatidylinositol-3,4,5-trisphosphate Binding Positive Regulation Of Organelle Organization Regulation Of Lymphocyte Activation Regulation Of Immune System Process Regulation Of Fibroblast Migration Response To Cytokine T Cell Costimulation Response To Peptide Postsynapse Positive Regulation Of Actin Filament Polymerization Hsp70 Protein Binding Protein Transport Positive Regulation Of Cellular Component Organization