TACR2

Description		tachykinin receptor 2
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GO Annotations	Cellular Component	Plasma Membrane Membrane Sperm Flagellum Sperm Head Sperm Midpiece
	Molecular Function	G Protein-coupled Receptor Activity Tachykinin Receptor Activity Protein Binding Substance K Receptor Activity
	Biological Process	Muscle Contraction Regulation Of Smooth Muscle Contraction Signal Transduction G Protein-coupled Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Positive Regulation Of Acetylcholine Secretion, Neurotransmission Intestine Smooth Muscle Contraction Negative Regulation Of Luteinizing Hormone Secretion Operant Conditioning Positive Regulation Of Vascular Permeability Positive Regulation Of Monoatomic Ion Transport Positive Regulation Of Smooth Muscle Contraction Response To Electrical Stimulus Prolactin Secretion Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Flagellated Sperm Motility
Pathways		Tachykinin receptors bind tachykinins G alpha (q) signalling events
Drugs		Saredutant
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: ANK3
Interacting Genes		5 interacting genes: GPRASP1 MTDH TAC1 TAC3 TAC4
Entrez ID		6865
HPRD ID		01207
Ensembl ID		ENSG00000075073
Uniprot IDs		P21452
PDB IDs		7XWO
Enriched GO Terms of Interacting Partners?		Substance K Receptor Binding Tachykinin Receptor Signaling Pathway Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Cilium Movement Regulation Of Flagellated Sperm Motility Substance P Receptor Binding Neuromedin K Receptor Binding Regulation Of Cilium Movement Regulation Of Microtubule-based Movement Positive Regulation Of Sensory Perception Of Pain Positive Regulation Of Reproductive Process Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Regulation Of Sensory Perception Of Pain Regulation Of Blood Pressure Detection Of Temperature Stimulus Involved In Sensory Perception Regulation Of Reproductive Process Negative Regulation Of Systemic Arterial Blood Pressure Detection Of Temperature Stimulus Regulation Of Microtubule-based Process Negative Regulation Of Blood Pressure Neuropeptide Signaling Pathway Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Maintenance Of Protein Location In Plasma Membrane Regulation Of Nervous System Process Positive Regulation Of Cell Motility G Protein-coupled Receptor Catabolic Process Bicellular Tight Junction Positive Regulation Of Locomotion Detection Of Abiotic Stimulus Receptor Ligand Activity Positive Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Corticosterone Secretion Detection Of Stimulus Involved In Sensory Perception Negative Regulation Of Sensory Perception Of Pain Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Temperature Stimulus Insemination Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential G Protein-coupled Receptor Signaling Pathway Cellular Response To Magnesium Ion Regulation Of Corticosterone Secretion Intercellular Canaliculus Channel Activator Activity Regulation Of Membrane Depolarization During Action Potential Negative Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Synaptic Transmission, Cholinergic Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Spectrin-associated Cytoskeleton Negative Regulation Of Voltage-gated Potassium Channel Activity Regulation Of Delayed Rectifier Potassium Channel Activity
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