AQR and RBM4

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		AQR	RBM4
Gene Name		aquarius intron-binding spliceosomal factor	RNA binding motif protein 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytoplasmic Stress Granule Nuclear Speck
	Molecular Function	Protein Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Zinc Ion Binding MiRNA Binding Poly(A) RNA Binding Pre-mRNA Intronic Binding Pre-mRNA Intronic Pyrimidine-rich Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Regulation Of Alternative MRNA Splicing, Via Spliceosome Cap-independent Translational Initiation IRES-dependent Translational Initiation RNA Processing MRNA Processing RNA Splicing Negative Regulation Of Translation Cell Differentiation Negative Regulation Of Translation In Response To Stress Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Translational Initiation Response To Arsenic-containing Substance Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Muscle Cell Differentiation Stress-activated MAPK Cascade Circadian Regulation Of Translation
Pathways
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		5 interactors: PQBP1 RBM22 RBM4 WDR77 WDR83	29 interactors: AQR CCNA1 CDK2 CXorf56 DDX17 DDX5 DGCR14 DHX9 HNRNPF HNRNPH2 HNRNPH3 HNRNPK HNRNPM HNRNPUL1 LRP2BP PABPC1 PRPF31 PTBP2 RBM10 RBM22 RBM23 RBM42 RBM7 SF1 SF3B4 SMAD5 SNRPC TRIB3 U2AF2
Entrez ID		9716	5936
HPRD ID		12468	03982
Ensembl ID		ENSG00000021776	ENSG00000173933
Uniprot IDs		O60306	Q9BWF3
PDB IDs			2DNQ
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Nitrogen Compound Metabolic Process Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development IRES-dependent Translational Initiation Cap-independent Translational Initiation Circadian Regulation Of Translation Negative Regulation Of Translation In Response To Stress Ribonucleoprotein Complex Biogenesis Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Cytoplasmic Translational Initiation Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Alternative MRNA Splicing, Via Spliceosome Regulation Of Intracellular Transport Cytoplasmic Translation Stress Granule Assembly Regulation Of Translation In Response To Stress MRNA Cis Splicing, Via Spliceosome Epithelial Cell Differentiation Involved In Prostate Gland Development Negative Regulation Of Translational Initiation Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Entrainment Of Circadian Clock By Photoperiod Regulation Of RNA Metabolic Process Photoperiodism Entrainment Of Circadian Clock Response To Arsenic-containing Substance Regulation Of Alternative MRNA Splicing, Via Spliceosome Protein Import Into Nucleus, Translocation Cellular Macromolecular Complex Assembly Positive Regulation Of RNA Splicing Gene Silencing By MiRNA Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Posttranscriptional Gene Silencing Spliceosomal SnRNP Assembly Glandular Epithelial Cell Differentiation Cellular Response To Drug Gene Silencing By RNA	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Processing Cellular Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of RNA Splicing Regulation Of Nitrogen Compound Metabolic Process MRNA Splice Site Selection Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Ribonucleoprotein Complex Assembly Spliceosomal Complex Assembly Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway MRNA Cis Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Ribonucleoprotein Complex Biogenesis MRNA Stabilization Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Spliceosomal SnRNP Assembly Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Meiotic Cell Cycle Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression
Tagcloud ?		adaptor adf afd arr arrestin asi balanced caenorhabditis chemosensory consequences deleterious elegans excessive gpcr gpcrs homeostasis immunity innate insufficient killing longevity microbial organismal pathogen played pqr thermosensory unfolded urx	ago2 altogether argonaute2 associates c2c12 cap colocalizes cytoplasm deposited entry granules micro micrornas microtubule mrnas myoblast notably participates potentiates recruit ribonucleoprotein ribonucleoproteins ribosome rnas suppress suppresses transiently translation translocates
Tagcloud (Difference) ?		adaptor adf afd arr arrestin asi balanced caenorhabditis chemosensory consequences deleterious elegans excessive gpcr gpcrs homeostasis immunity innate insufficient killing longevity microbial organismal pathogen played pqr thermosensory unfolded urx	ago2 altogether argonaute2 associates c2c12 cap colocalizes cytoplasm deposited entry granules micro micrornas microtubule mrnas myoblast notably participates potentiates recruit ribonucleoprotein ribonucleoproteins ribosome rnas suppress suppresses transiently translation translocates
Tagcloud (Intersection) ?