RBM4 and LRP2BP

Number of citations of the paper that reports this interaction (PMID 12508107)
4

Data Source:
HPRD (two hybrid)

		RBM4	LRP2BP
Gene Name		RNA binding motif protein 4	LRP2 binding protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytoplasmic Stress Granule Nuclear Speck	Cytoplasm
	Molecular Function	Nucleotide Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Zinc Ion Binding MiRNA Binding Poly(A) RNA Binding Pre-mRNA Intronic Binding Pre-mRNA Intronic Pyrimidine-rich Binding	Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Cap-independent Translational Initiation IRES-dependent Translational Initiation RNA Processing MRNA Processing RNA Splicing Negative Regulation Of Translation Cell Differentiation Negative Regulation Of Translation In Response To Stress Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Translational Initiation Response To Arsenic-containing Substance Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Muscle Cell Differentiation Stress-activated MAPK Cascade Circadian Regulation Of Translation
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		29 interactors: AQR CCNA1 CDK2 CXorf56 DDX17 DDX5 DGCR14 DHX9 HNRNPF HNRNPH2 HNRNPH3 HNRNPK HNRNPM HNRNPUL1 LRP2BP PABPC1 PRPF31 PTBP2 RBM10 RBM22 RBM23 RBM42 RBM7 SF1 SF3B4 SMAD5 SNRPC TRIB3 U2AF2	7 interactors: BAI2 COPS3 LRP2 PICK1 RBM4 SNW1 TSC22D4
Entrez ID		5936	55805
HPRD ID		03982	10911
Ensembl ID		ENSG00000173933	ENSG00000109771
Uniprot IDs		Q9BWF3	Q9P2M1
PDB IDs		2DNQ
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Processing Cellular Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of RNA Splicing Regulation Of Nitrogen Compound Metabolic Process MRNA Splice Site Selection Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Ribonucleoprotein Complex Assembly Spliceosomal Complex Assembly Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway MRNA Cis Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Ribonucleoprotein Complex Biogenesis MRNA Stabilization Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Spliceosomal SnRNP Assembly Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Meiotic Cell Cycle Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression	Response To Abiotic Stimulus Response To Light Stimulus Regulation Of MRNA Splicing, Via Spliceosome Response To Radiation Regulation Of MRNA Processing Regulation Of RNA Splicing Positive Regulation Of Vitamin D Receptor Signaling Pathway Response To Stimulus Signal Transduction Developmental Process Signaling Cell Communication IRES-dependent Translational Initiation Cap-independent Translational Initiation Regulation Of Gene Expression, Epigenetic Regulation Of Vitamin D Receptor Signaling Pathway Circadian Regulation Of Translation DNA Methylation Involved In Embryo Development Nervous System Development Negative Regulation Of Translation In Response To Stress Cullin Deneddylation Cellular Response To Stimulus Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Dendritic Spine Maintenance Cytoplasmic Translational Initiation Positive Regulation By Host Of Viral Transcription Protein Deneddylation Neuronal Ion Channel Clustering Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Vitamin D Metabolic Process Negative Regulation Of Actin Nucleation RNA Splicing Multicellular Organismal Development Cytoplasmic Translation Positive Regulation Of Histone H3-K4 Methylation Regulation Of Translation In Response To Stress Negative Regulation Of Gene Expression Long Term Synaptic Depression Negative Regulation Of Biosynthetic Process Anatomical Structure Development Positive Regulation Of Receptor Internalization Negative Regulation Of Translational Initiation Regulation Of Arp2/3 Complex-mediated Actin Nucleation MRNA Processing Dendritic Spine Organization Entrainment Of Circadian Clock By Photoperiod DNA Methylation Involved In Gamete Generation Regulation Of Histone H3-K4 Methylation Regulation Of Actin Nucleation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?		ago2 altogether argonaute2 associates c2c12 cap colocalizes cytoplasm deposited entry granules micro micrornas microtubule mrnas myoblast notably participates potentiates recruit ribonucleoprotein ribonucleoproteins ribosome rnas suppress suppresses transiently translation translocates
Tagcloud (Difference) ?		ago2 altogether argonaute2 associates c2c12 cap colocalizes cytoplasm deposited entry granules micro micrornas microtubule mrnas myoblast notably participates potentiates recruit ribonucleoprotein ribonucleoproteins ribosome rnas suppress suppresses transiently translation translocates
Tagcloud (Intersection) ?